anti- BIN1 antibody

• Catalog number
  FNab00897
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
• Immunogen
  bridging integrator 1
• Synonyms
  AMPHL
• Calculated MW
  65 kDa
• Uniprot ID
  O00499
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC, IF
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:50
• Image1
  Immunohistochemistry of paraffin-embedded human osteosarcoma using FNab00897(BIN1 antibody) at dilution of 1:100
• Image4
  Jurkat cells were subjected to SDS PAGE followed by western blot with FNab00897(BIN1 antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BIN1  
• Gene symbol
  BIN1
• Short name
  anti- BIN1 antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- bridging integrator 1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  bridging integrator 1, AMPH2 and AMPHL and SH3P9, BIN1 and IDBG-68691 and ENSG00000136717 and 274, GTPase binding, nuclei, Bin1 and IDBG-133763 and ENSMUSG00000024381 and 30948, BIN1 and IDBG-639275 and ENSBTAG00000019177 and 614576

Gene info

• Identity
  HGNC:1052
• Gene
  BIN1
• Long gene name
  bridging integrator 1
• Synonyms gene
  • AMPHL
• Synonyms
  • SH3P9
  • AMPH2
• Synonyms name
  • amphiphysin II
• GenBank acession
  • U68485
• Locus
  2q14.3
• Discovery year
  2000-05-19
• Entrez gene record
  274
• Pubmed identfication
  • 8725406
  • 8782822
  • 17676042
• RefSeq identity
  • NM_139343
• Classification
  • N-BAR domain containing
• VEGA ID
  OTTHUMG00000131465
• Locus Specific Databases
  • LRG_873

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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