TPX2 monoclonal antibody

• Catalog number
  11-818-C100
• Price
  Please ask
• Size
  100ug

• Long name
  Mouse Monoclonal Antibody against Human TPX2, Clone: TPX2-01
• Antigen
  TPX2
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  TPX2-01
• Applications
  IP, WB, IHC(P), ICC, ELISA
• Immunogen
  Human TPX2
• Format conjugation
  purified; unconjugated
• Specificity
  The mouse monoclonal antibody TPX2-01 recognizes the epitope EPFVPKKEKKS (aa 636-646 in human) of TPX2, a microtubule-associated critical regulator of mitosis, which is overexpressed in many types of tumors and is a marker of worse prognosis in various cancers.
• Research area
  Cytoskeleton: Tubulin System (Human)
• Concentration
  1 mg/ml
• Storage buffer
  Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
• Shipping and storage
  Mouse Monoclonal Antibody against Human TPX2, Clone: TPX2-01 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  TPX2 is a microtubule-associated protein, which is a critical regulator of mitosis. At the beginning of mitosis, TPX2 is released and plays a significant role in mitotic spindle formation and subsequent proper segregation of chromosomes during cell division. After completion of mitosis the TPX2 protein disappears, but has also role in DNA damage response. Its overexpression has been demonstrated in many types of carcinomas. TPX2 belongs to the markers of worse tumor prognosis. On the other hand, down-regulation of TPX2 can inhibit cancer cell proliferation, migration and invasion.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified from hybridoma culture supernatant by protein-A affinity chromatography.
• Datasheet
• References
  Contact us for the most recent list of references
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  TPX2   monoclonal  
• Gene symbol
  TPX2
• Short name
  Anti-TPX2 Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgG1
• Alternative name
  Mouse Monoclonal to TPX2
• Alternative technique
  antibodies
• Alternative to gene target
  TPX2, microtubule-associated, homolog (Xenopus laevis), C20orf1 and C20orf2 and DIL-2 and DIL2 and FLS353 and GD:C20orf1 and HCA519 and HCTP4 and p100 and REPP86, TPX2 and IDBG-63816 and ENSG00000088325 and 22974, protein kinase binding, nuclei, Tpx2 and IDBG-209892 and ENSMUSG00000027469 and 72119, BT.28741 and IDBG-641544 and ENSBTAG00000018775 and 507226

Gene info

• Identity
  HGNC:1249
• Gene
  TPX2
• Long gene name
  TPX2 microtubule nucleation factor
• Synonyms gene
  • C20orf2
  • C20orf1
• Synonyms gene name
  • chromosome 20 open reading frame 1
  • TPX2, microtubule-associated, homolog (Xenopus laevis)
  • TPX2, microtubule-associated
• Synonyms
  • p100
  • DIL-2
• GenBank acession
  • AF098158
• Locus
  20q11.21
• Discovery year
  1999-09-29
• Entrez gene record
  22974
• Pubmed identfication
  • 9207457
  • 10393424
• VEGA ID
  OTTHUMG00000032190

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products