DDIT4L monoclonal antibody

• Catalog number
  11-725-C100
• Price
  Please ask
• Size
  100ug

• Long name
  Mouse Monoclonal Antibody against Human DDIT4L, Clone: DDIT-03
• Antigen
  DDIT4L
• Species reactivity
  Human (Homo sapiens)
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  DDIT-03
• Applications
  FC, WB
• Immunogen
  N-terminal recombinant fragment of human DDIT4L (amino acids 2-98)
• Format conjugation
  purified; unconjugated
• Specificity
  The mouse monoclonal antibody DDIT-03 recognizes DDIT4L / REDD2 protein, which belongs to stress-induced proteins involved in mediation of cell death.
• Research area
  Apoptosis (Human)
• Concentration
  1 mg/ml
• Storage buffer
  Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
• Shipping and storage
  Mouse Monoclonal Antibody against Human DDIT4L, Clone: DDIT-03 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by protein-A affinity chromatography
• Datasheet
• References
  Contact us for the most recent list of references
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  DDIT4L   monoclonal  
• Gene symbol
  DDIT4L-AS1, DDIT4L
• Short name
  Anti-DDIT4L Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgG1
• Alternative name
  Mouse Monoclonal to DDIT4L
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:55562
• Gene
  DDIT4L-AS1
• Long gene name
  DDIT4L antisense RNA 1
• Locus
  4q24
• Discovery year
  2021-04-14
• Entrez gene record
  101929353
• RefSeq identity
  • NR_125924
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:30555
• Gene
  DDIT4L
• Long gene name
  DNA damage inducible transcript 4 like
• Synonyms gene name
  • DNA-damage-inducible transcript 4-like
• Synonyms
  • REDD2
  • Rtp801L
• Synonyms name
  • regulated in development and DNA damage response 2
  • similar to Smhs1 protein
• GenBank acession
  • BC013592
• Locus
  4q24
• Discovery year
  2004-02-12
• Entrez gene record
  115265
• Pubmed identfication
  • 28246202
• RefSeq identity
  • NM_145244
• VEGA ID
  OTTHUMG00000161019

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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