CtBP1 / BARS PAb

• Catalog number
  11-511-C100
• Price
  Please ask
• Size
  100ug

• Long name
  Rabbit Polyclonal Antibody against Human CtBP1 / BARS, Clone: PAb
• Antigen
  CtBP1
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus)
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Polyclonal Antibody (PAb)
• Clone
  Polyclonal
• Applications
  IP, WB, ICC
• Immunogen
  Bacterially expressed full-length human CtBP1
• Format conjugation
  purified; unconjugated
• Specificity
  The polyclonal antibody reacts with CtBP1, a 49 kDa transcriptional corepressor, that plays a critical role in regulating gene expression.
• Research area
  Transcription Regulation & Nuclear Proteins (Rodent), Transcription Regulation & Nuclear Proteins (Human), Transcription Regulation & Nuclear Proteins
• Concentration
  1 mg/ml
• Storage buffer
  Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
• Shipping and storage
  Rabbit Polyclonal Antibody against Human CtBP1 / BARS, Clone: PAb is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  C-terminal binding protein 1 / brefeldin A (BFA)-dependent ADP-ribosylation substrate (CtBP1/BARS) is a highly conserved transcriptional corepressor, that plays a critical role in regulating gene expression patterns throughout development and in oncogenesis. CtBP regulates target gene transcription, in part, via recruitment of histone deacetylases involved in gene silencing and may act to coordonate histone modifications that regulate gene expression.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified from rabbit serum by affinity chromatography
• Datasheet
• References
  *Valenta T, Lukas J, Doubravska L, Fafilek B, Korinek V.: HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. EMBO J. 2006 Jun 7;25(11):2326-37.

• Gene target
  CtBP1   BARS   PAb  
• Gene symbol
  CTBP1
• Short name
  Anti-CtBP1 / BARS PAb
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  IgG (various subtypes)
• Alternative name
  Rabbit Polyclonal to CtBP1 / BARS
• Alternative to gene target
  C-terminal binding protein 1, BARS, CTBP1 and IDBG-6522 and ENSG00000159692 and 1487, oxidoreductase activity, nuclei, Ctbp1 and IDBG-152845 and ENSMUSG00000037373 and 13016, CTBP1 and IDBG-643874 and ENSBTAG00000008480 and 513131

Gene info

• Identity
  HGNC:2494
• Gene
  CTBP1
• Long gene name
  C-terminal binding protein 1
• Synonyms
  • BARS
• Synonyms name
  • brefeldin A-ribosylated substrate
• GenBank acession
  • U37408
• Locus
  4p16.3
• Discovery year
  1997-08-22
• Entrez gene record
  1487
• Pubmed identfication
  • 9479502
• RefSeq identity
  • NM_001328
• VEGA ID
  OTTHUMG00000089259

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