CRP monoclonal antibody

• Catalog number
  11-484-C100
• Price
  Please ask
• Size
  100ug

• Long name
  Mouse Monoclonal Antibody against Human CRP, Clone: C7
• Antigen
  CRP
• Species reactivity
  Human (Homo sapiens)
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  C7
• Applications
  ELISA
• Immunogen
  Purified human CRP
• Format conjugation
  purified; unconjugated
• Specificity
  The antibody C7 recognizes human CRP, an 117 kDa acute phase protein; it recognizes antigen both in the presence and in the absence (samples containing EDTA) of Ca2+.
• Research area
  Transcription Regulation & Nuclear Proteins (Human), Transcription Regulation & Nuclear Proteins, Serum & Plasma Proteins (Human)
• Concentration
  1 mg/ml
• Storage buffer
  Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
• Shipping and storage
  Mouse Monoclonal Antibody against Human CRP, Clone: C7 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  The C-reactive protein (CRP) is a cyclic pentameric pentraxin family acute phase protein compound of five identical noncovalently bound nonglycosylated subunits (each subunit 24 kDa; physiologic CRP molecule 117,5 kDa). CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes occuring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.) and is also believed to play an important role in innate immunity. Patients with elevated basal levels of CRP are at increased risk for hypertension and cardiovascular disease.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by protein-A affinity chromatography
• Datasheet
• References
  *Krämer PM, Kess M, Kremmer E, Schulte-Hostede S: Multi-parameter determination of TNFα, PCT and CRP for point-of-care testing. Analyst. 2011 Feb 21;136(4):692-5.
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Gene
  C reactive proteins are detected by anti-CRP antibodies supplied by GENTAUR.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  CRP   monoclonal  
• Gene symbol
  CRP, PPIAP10
• Short name
  Anti-CRP Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgG1
• Alternative name
  Mouse Monoclonal to CRP
• Alternative technique
  antibodies
• Alternative to gene target
  C-reactive protein, pentraxin-related, PTX1, CRP and IDBG-103911 and ENSG00000132693 and 1401, protein homodimerization activity, Extracellular, Crp and IDBG-205690 and ENSMUSG00000037942 and 12944, CRP and IDBG-630749 and ENSBTAG00000013907 and 527553

Gene info

• Identity
  HGNC:2367
• Gene
  CRP
• Long gene name
  C-reactive protein
• Synonyms gene name
  • C-reactive protein, pentraxin-related
• Synonyms
  • PTX1
• Synonyms name
  • pentraxin 1
• GenBank acession
  • M11725
• Locus
  1q23.2
• Discovery year
  2001-06-22
• Entrez gene record
  1401
• Pubmed identfication
  • 3840479
  • 6857266
• RefSeq identity
  • NM_000567
• Classification
  • Short pentraxins
• VEGA ID
  OTTHUMG00000035344

Gene info

• Identity
  HGNC:9264
• Gene
  PPIAP10
• Long gene name
  peptidylprolyl isomerase A pseudogene 10
• Synonyms gene
  • PPIAL2
  • PPIP10
• Synonyms gene name
  • peptidylprolyl isomerase A (cyclophilin A)-like 2
  • peptidylprolyl isomerase (cyclophilin) pseudogene 10
• Synonyms
  • CRP
• Synonyms name
  • cyclophillin related pseudogene
• GenBank acession
  • AL354993
• Locus
  20q13.2
• Discovery year
  1998-10-12
• Entrez gene record
  140913
• Pubmed identfication
  • 9671742
• RefSeq identity
  • NG_001008
• VEGA ID
  OTTHUMG00000032762

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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