-
Long name
Mouse Monoclonal Antibody against Human CD99R, Clone: MEM-131
-
Antigen
CD99R
-
Species reactivity
Human (Homo sapiens)
-
Negative species reactivity
at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
-
Clonality
Monoclonal Antibody (Mab)
-
Clone
MEM-131
-
Applications
FC, IP, WB, IHC(P)
-
Immunogen
HPB-ALL human peripheral blood leukemia T-cell line
-
Format conjugation
FITC
-
Specificity
The antibody MEM-131 reacts with CD99R, an epitope restricted to a subset of CD99 molecule expressed on myeloid cells, NK cells and T lymphocytes._x000D_ HLDA V; WS Code AS S020 _x000D_ HLDA V; WS Code T T-E2.02 _x000D_ HLDA V; WS Code T T-017 _x000D_ _x000D_ _x000D_
-
Research area
CD and Related Antigens (Human)
-
Storage buffer
The reagent is provided in stabilizing Tris buffered saline (TBS) solution containing 15 mM sodium azide.
-
Shipping and storage
Mouse Monoclonal Antibody against Human CD99R, Clone: MEM-131 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
-
Background
CD99 (E2, MIC2) is a transmembrane glycoprotein that is involved in regulation of T cell addhesive properties and programmed cell death distinct from typical apoptosis course. CD99 roles are specific to certain stages of T cell differentiation such as corticothymocytes. CD99R isoform expression is restricted in the haematopoietic system to T, NK and myeloid cells.
-
Purity
> 95% (by SDS-PAGE)
-
Purification method
Purified by affinity chromatography
-
-
References
*Cermak L, Simova S, Pintzas A, Horejsi V, Andera L: Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules. J Biol Chem. 2002 Mar 8;277(10):7955-61. _x000D_ , *Olweus J, Lund-Johansen F, Terstappen LW: CD64/Fc gamma RI is a granulo-monocytic lineage marker on CD34+ hematopoietic progenitor cells. Blood. 1995 May 1;85(9):2402-13., *Leukocyte Typing V., Schlossman S. et al. (Eds.), Oxford University Press (1995).
-
Properties
If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
French translation
anticorps
