CD97 monoclonal antibody

• Catalog number
  1F-267-T100
• Price
  Please ask
• Size
  100 assays

• Long name
  Mouse Monoclonal Antibody against Human CD97, Clone: MEM-180
• Antigen
  CD97
• Species reactivity
  Human (Homo sapiens)
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  MEM-180
• Applications
  FC, IP
• Immunogen
  PHA-activated peripheral blood cells
• Format conjugation
  FITC
• Specificity
  The antibody MEM-180 recognizes a unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes._x000D_ HLDA VI; WS Code BP 415 _x000D_ HLDA VI; WS Code NL N-L023 _x000D_ _x000D_ _x000D_
• Research area
  CD and Related Antigens (Human)
• Storage buffer
  The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
• Shipping and storage
  Mouse Monoclonal Antibody against Human CD97, Clone: MEM-180 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by affinity chromatography
• Datasheet
• References
  *Wobus M, Vogel B, Schmücking E, Hamann J, Aust G: N-glycosylation of CD97 within the EGF domains is crucial for epitope accessibility in normal and malignant cells as well as CD55 ligand binding. Int J Cancer. 2004 Dec 10;112(5):815-22., *Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997).
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  CD97   monoclonal  
• Gene symbol
  ADGRE5
• Short name
  Anti-CD97 Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgG1
• Alternative name
  Mouse Monoclonal to CD97
• Alternative technique
  antibodies
• Alternative to gene target
  CD97 molecule, TM7LN1, CD97 and IDBG-33120 and ENSG00000123146 and 976, protein binding, Extracellular, Cd97 and IDBG-172600 and ENSMUSG00000002885 and 26364, CD97 and IDBG-642684 and ENSBTAG00000021818 and 338066

Gene info

• Identity
  HGNC:1711
• Gene
  ADGRE5
• Long gene name
  adhesion G protein-coupled receptor E5
• Synonyms gene
  • CD97
• Synonyms gene name
  • CD97 antigen
  • CD97 molecule
• Synonyms
  • TM7LN1
• Synonyms name
  • leukocyte antigen CD97
  • seven-span transmembrane protein
  • seven-transmembrane, heterodimeric receptor associated with inflammation
  • seven transmembrane helix receptor
• Locus
  19p13.12
• Discovery year
  1995-11-29
• Entrez gene record
  976
• Pubmed identfication
  • 7636245
  • 8786105
  • 25713288
• RefSeq identity
  • NM_078481
• Classification
  • CD molecules
  • Adhesion G protein-coupled receptors, subfamily E
• VEGA ID
  OTTHUMG00000182166

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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