CD7 monoclonal antibody

• Catalog number
  T9-206-T025
• Price
  Please ask
• Size
  25 assays

• Long name
  Mouse Monoclonal Antibody against Human CD7, Clone: MEM-186
• Antigen
  CD7
• Species reactivity
  Human (Homo sapiens)
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  MEM-186
• Applications
  FC, IP, WB, IHC(P)
• Immunogen
  Human acute myelogenous leukaemia cell line KG-1.
• Format conjugation
  PerCP-Cy 5.5
• Specificity
  The MEM-186 antibody reacts with CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.HLDA VI; WS Code T 6T-015_x000D_
• Research area
  CD and Related Antigens (Human)
• Storage buffer
  The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
• Shipping and storage
  Mouse Monoclonal Antibody against Human CD7, Clone: MEM-186 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by affinity chromatography
• Datasheet
• References
  *Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997).
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  CD7   monoclonal  
• Gene symbol
  CD7
• Short name
  Anti-CD7 Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgG1
• Alternative name
  Mouse Monoclonal to CD7
• Alternative technique
  antibodies
• Alternative to gene target
  CD7 molecule, GP40 and LEU-9 and Tp40 and TP41, CD7 and IDBG-73437 and ENSG00000173762 and 924, protein binding, Plasma membranes, Cd7 and IDBG-214932 and ENSMUSG00000025163 and 12516, CD7 and IDBG-642137 and ENSBTAG00000011359 and 510073

Gene info

• Identity
  HGNC:1695
• Gene
  CD7
• Long gene name
  CD7 molecule
• Synonyms gene name
  • CD7 antigen (p41)
• Synonyms
  • GP40
  • LEU-9
  • TP41
  • Tp40
• Synonyms name
  • p41 protein
  • T-cell antigen CD7
  • T-cell leukemia antigen
• GenBank acession
  • X06180
• Locus
  17q25.3
• Discovery year
  1986-01-01
• Entrez gene record
  924
• Pubmed identfication
  • 1695199
  • 3501369
• RefSeq identity
  • NM_006137
• Classification
  • CD molecules
  • V-set domain containing
• VEGA ID
  OTTHUMG00000178662

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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