CD69 monoclonal antibody
-
Catalog numberA6-552-T100
-
PricePlease ask
-
Size100 assays
-
-
Long nameMouse Monoclonal Antibody against Human CD69, Clone: FN50
-
AntigenCD69
-
Species reactivityHuman (Homo sapiens), Other not determined
-
Negative species reactivityat the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
-
ClonalityMonoclonal Antibody (Mab)
-
CloneFN50
-
ApplicationsFC, IHC(F), FUNC
-
Immunogenanti-µ-stimulated human B lymphocytes_x000D_
-
Format conjugationAlexa Fluor 647
-
SpecificityThe antibody FN50 recognizes CD69, an lymphocyte early activation marker._x000D_ HLDA IV; WS Code A 91 _x000D_
-
Research areaCD and Related Antigens (Human)
-
Storage bufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
-
Shipping and storageMouse Monoclonal Antibody against Human CD69, Clone: FN50 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
-
BackgroundCD69 (C-type lectin domain family 2 C, CLEC2C, also known as AIM) is one of the earliest inducible cell surface molecules acquired during leukocyte activation. This glycoprotein serves as a lectin-type receptor in lymphocytes, NK cells and platelets; it is involved in lymphocyte proliferation. CD69 expression is counteracted on T cells in the AIDS stage of HIV infection, and may be also predictive for clinical response to chemoimmunotherapy._x000D_
-
Purity> 95% (by SDS-PAGE)
-
Purification methodPurified by affinity chromatography
-
References*Hrdinka M, Dráber P, Stepánek O, Ormsby T, Otáhal P, Angelisová P, Brdicka T, Paces J, Horejsí V, Drbal K: PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis. J Biol Chem. 2011 Jun 3;286(22):19617-29., *Tomescu C, Chehimi J, Maino VC, Montaner LJ: NK cell lysis of HIV-1-infected autologous CD4 primary T cells: requirement for_x000D_ IFN-mediated NK activation by plasmacytoid dendritic cells. J Immunol. 2007 Aug 15;179(4):2097-104., *Drbal K, Moertelmaier M, Holzhauser C, Muhammad A, Fuertbauer E, Howorka S, Hinterberger M, Stockinger H, Schütz GJ: Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement. Int Immunol. 2007 May;19(5):675-84., *Leukocyte Typing IV., Knapp W. et al. (Eds.), Oxford University Press (1989); p. 293.
-
PropertiesIf you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
-
French translationanticorps
-
Gene target
-
Gene symbolCD69
-
Short nameAnti-CD69 Mab
-
TechniqueAntibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
-
HostMouse (Mus musculus)
-
IsotypeIgG1
-
Alternative nameMouse Monoclonal to CD69
-
Alternative techniqueantibodies
-
Alternative to gene targetCD69 molecule, AIM and BL-AC/P26 and CLEC2C and EA1 and GP32/28 and MLR-3, CD69 and IDBG-18077 and ENSG00000110848 and 969, carbohydrate binding, Cell surfaces, Cd69 and IDBG-191849 and ENSMUSG00000030156 and 12515, CD69 and IDBG-639618 and ENSBTAG00000002135 and 281058
-
Gene info
-
Identity
-
Gene
-
Long gene nameCD69 molecule
-
Synonyms gene name
- CD69 antigen (p60, early T-cell activation antigen)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1992-08-06
-
Entrez gene record
-
Pubmed identfication
-
Classification
- C-type lectin domain containing
- CD molecules
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data