CD267 / TACI monoclonal antibody

• Catalog number
  11-162-C025
• Price
  Please ask
• Size
  25ug

• Long name
  Rat Monoclonal Antibody against Human CD267 / TACI, Clone: 1A1
• Antigen
  CD267 / TACI
• Species reactivity
  Human (Homo sapiens)
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  1A1
• Applications
  FC
• Immunogen
  CD267-transfected RBL cells
• Format conjugation
  purified; unconjugated
• Specificity
  The rat monoclonal antibody 1A1 recognizes CD267 / TACI, a 32 kDa type III transmembrane protein expressed by B cells and possibly by some activated T cells._x000D_ _x000D_ HLDA 8 Workshop
• Research area
  CD and Related Antigens (Human)
• Concentration
  1 mg/ml
• Storage buffer
  Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
• Shipping and storage
  Rat Monoclonal Antibody against Human CD267 / TACI, Clone: 1A1 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  CD267 / TACI (Transmembrane Activator Calcium modulator and cyclophilin ligand Interactor), a TNFR superfamily transmembrane protein, is expressed on B cells (predominantly on CD27+ memory cells), multiple myeloma cells and B cell chronic lymphocytic leukemia (B-CLL). Its triggering leads to activation of the transcription factors NFAT, AP1, and NF-kappa-B. It plays a crucial role in humoral immunity. Mutations in CD267 are associated with common variable immunodeficiency and IgA deficiency.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by protein-A affinity chromatography
• Datasheet
• References
  *Koarada S, Tada Y, Suematsu R, Soejima S, Inoue H, Ohta A, Nagasawa K: Phenotyping of P105-negative B cell subsets in patients with systemic lupus erythematosus. Clin Dev Immunol. 2012;2012:198206.
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  CD267   TACI   monoclonal  
• Gene symbol
  TNFRSF13B
• Short name
  Anti-CD267 / TACI Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Rat (Rattus norvegicus)
• Isotype
  IgG2a
• Alternative name
  Rat Monoclonal to CD267 / TACI
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18153
• Gene
  TNFRSF13B
• Long gene name
  TNF receptor superfamily member 13B
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 13B
• Synonyms
  • TACI
  • CD267
  • IGAD2
• GenBank acession
  • AF023614
• Locus
  17p11.2
• Discovery year
  2002-05-22
• Entrez gene record
  23495
• Pubmed identfication
  • 9311921
• Classification
  • CD molecules
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000059262
• Locus Specific Databases
  • TNFRSF13Bbase: Mutation registry for TACI deficiency
  • LRG_120

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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