CD163 monoclonal antibody

• Catalog number
  11-645-C100
• Price
  Please ask
• Size
  100ug

• Long name
  Mouse Monoclonal Antibody against Human CD163, Clone: GHI/61
• Antigen
  CD163
• Species reactivity
  Human (Homo sapiens)
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  GHI/61
• Applications
  FC, IP, WB, IHC(F)
• Immunogen
  Hairy cell leukemia cells
• Format conjugation
  purified; unconjugated
• Specificity
  The mouse monoclonal antibody GHI/61 recognizes CD163, an approximately 130 kDa high affinity scavenger receptor expressed mainly on monocytes and macrophages, which binds hemoglobin-haptoglobin complex._x000D_ _x000D_ HLDA VI; WS Code M38
• Research area
  CD and Related Antigens (Human)
• Concentration
  1 mg/ml
• Storage buffer
  Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
• Shipping and storage
  Mouse Monoclonal Antibody against Human CD163, Clone: GHI/61 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by protein-A affinity chromatography
• Datasheet
• References
  Contact us for the most recent list of references
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  CD163   monoclonal  
• Gene symbol
  CD163
• Short name
  Anti-CD163 Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgG1
• Alternative name
  Mouse Monoclonal to CD163
• Alternative technique
  antibodies
• Alternative to gene target
  CD163 molecule, M130 and MM130, CD163 and IDBG-16292 and ENSG00000177575 and 9332, protein binding, Extracellular, Cd163 and IDBG-186721 and ENSMUSG00000008845 and 93671, CD163 and IDBG-639861 and ENSBTAG00000019669 and 533844

Gene info

• Identity
  HGNC:1631
• Gene
  CD163
• Long gene name
  CD163 molecule
• Synonyms gene name
  • CD163 antigen
• Synonyms
  • M130
  • MM130
  • SCARI1
• GenBank acession
  • Z22968
• Locus
  12p13.31
• Discovery year
  2000-01-18
• Entrez gene record
  9332
• Pubmed identfication
  • 10403791
  • 8370408
• RefSeq identity
  • NM_004244
  • NM_203416
• Classification
  • CD molecules
  • Scavenger receptors
  • Scavenger receptor cysteine rich domain containing
• VEGA ID
  OTTHUMG00000168353

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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