CD10 / CALLA monoclonal antibody

• Catalog number
  11-413-C100
• Price
  Please ask
• Size
  100ug

• Long name
  Mouse Monoclonal Antibody against Human CD10 / CALLA, Clone: LT10
• Antigen
  CD10
• Species reactivity
  Other not tested, Human (Homo sapiens)
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  LT10
• Applications
  FC
• Immunogen
  mouse NALM-6 leukemia pre-B cell line (tissue/cell preparation)
• Format conjugation
  purified; unconjugated
• Specificity
  The antibody LT10 reacts with CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.
• Research area
  CD and Related Antigens (Human)
• Concentration
  1 mg/ml
• Storage buffer
  Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
• Shipping and storage
  Mouse Monoclonal Antibody against Human CD10 / CALLA, Clone: LT10 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  CD10 (neutral endopeptidase – NEP, common acute lymphocytic leukemia antigen – CALLA, membrane metallo-endopeptidase – MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by precipitation and chromatography
• Datasheet
• References
  *Leukocyte Typing VII., Mason D. et al. (Eds.), Oxford University Press (2002).
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  CD10   CALLA   monoclonal  
• Gene symbol
  MME
• Short name
  Anti-CD10 / CALLA Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgG1
• Alternative name
  Mouse Monoclonal to CD10 / CALLA
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7154
• Gene
  MME
• Long gene name
  membrane metalloendopeptidase
• Synonyms
  • CALLA
  • CD10
  • NEP
• Synonyms name
  • neutral endopeptidase
  • enkephalinase
  • neprilysin
• Locus
  3q25.2
• Discovery year
  1989-05-15
• Entrez gene record
  4311
• RefSeq identity
  • NM_000902
• Classification
  • M13 metallopeptidases
  • CD molecules
• VEGA ID
  OTTHUMG00000158455

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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