AGR2+AGR3 monoclonal antibody

• Catalog number
  11-562-C100
• Price
  Please ask
• Size
  100ug

• Long name
  Mouse Monoclonal Antibody against Human AGR2+AGR3, Clone: AGR3.4
• Antigen
  AGR2+AGR3
• Species reactivity
  Human (Homo sapiens), Other species Not tested
• Negative species reactivity
  at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
• Clonality
  Monoclonal Antibody (Mab)
• Clone
  AGR3.4
• Applications
  WB, IHC(P), ICC
• Immunogen
  Purified human AGR3 protein_x000D_
• Format conjugation
  purified; unconjugated
• Specificity
  The antibody AGR3.4 recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa); secreted cytoplasmic proteins which can serve as markers of carcinogenesis. _x000D_
• Research area
  Serum & Plasma Proteins (Human)
• Concentration
  1 mg/ml
• Storage buffer
  The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
• Shipping and storage
  Mouse Monoclonal Antibody against Human AGR2+AGR3, Clone: AGR3.4 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
• Background
  AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours; AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development._x000D_
• Purity
  > 95% (by SDS-PAGE)
• Purification method
  Purified by protein-A affinity chromatography
• Datasheet
• References
  Contact us for the most recent list of references
• Properties
  If you buy Antibodies supplied by Exbio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• French translation
  anticorps

• Gene target
  AGR2+AGR3   monoclonal  
• Gene symbol
  AGR3, AGR2
• Short name
  Anti-AGR2+AGR3 Mab
• Technique
  Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
• Host
  Mouse (Mus musculus)
• Isotype
  IgG1
• Alternative name
  Mouse Monoclonal to AGR2+AGR3
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:24167
• Gene
  AGR3
• Long gene name
  anterior gradient 3, protein disulphide isomerase family member
• Synonyms gene name
  • anterior gradient 3 homolog (Xenopus laevis)
• Synonyms
  • HAG3
  • hAG-3
  • BCMP11
  • PDIA18
• Synonyms name
  • breast cancer membrane protein 11
  • protein disulfide isomerase family A, member 18
• GenBank acession
  • AY069977
• Locus
  7p21.1
• Discovery year
  2007-02-05
• Entrez gene record
  155465
• Pubmed identfication
  • 12592373
• RefSeq identity
  • NM_176813
• Classification
  • Protein disulfide isomerases
• VEGA ID
  OTTHUMG00000128411

Gene info

• Identity
  HGNC:328
• Gene
  AGR2
• Long gene name
  anterior gradient 2, protein disulphide isomerase family member
• Synonyms gene name
  • anterior gradient 2 homolog (Xenopus laevis)
• Synonyms
  • XAG-2
  • HAG-2
  • AG2
  • PDIA17
• Synonyms name
  • protein disulfide isomerase family A, member 17
• GenBank acession
  • AF038451
• Locus
  7p21.1
• Discovery year
  2000-03-06
• Entrez gene record
  10551
• Pubmed identfication
  • 9790916
• RefSeq identity
  • NM_006408
• Classification
  • Protein disulfide isomerases
• VEGA ID
  OTTHUMG00000023446

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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