ICOS ligand

Conjugation

Alexa Fluor 450M
Note

For research use only.
Description

FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.

Gene target

ICOS ligand
Gene symbol

ICOS, ICOSLG
Short name

ICOS ligand
Alternative name

inducible T-cell co-stimulator ligand
Alternative to gene target

inducible T-cell co-stimulator, ICOS and IDBG-79246 and ENSG00000163600 and 29851, protein binding, Extracellular, Icos and IDBG-159737 and ENSMUSG00000026009 and 54167, ICOS and IDBG-643378 and ENSBTAG00000021596 and 507026

Identity

HGNC:5351
Gene

ICOS
Long gene name

inducible T cell costimulator
Synonyms gene name
- inducible T-cell costimulator
Synonyms
- AILIM
- CD278
Synonyms name
- activation-inducible lymphocyte immunomediatory molecule
GenBank acession
- AB023135
Locus

2q33.2
Discovery year

2000-02-29
Entrez gene record

29851
Pubmed identfication
- 9930702
- 10617205
RefSeq identity
- NM_012092
Classification
- CD molecules
VEGA ID

OTTHUMG00000132880
Locus Specific Databases
- ICOSbase: Mutation registry for ICOS deficiency
- LRG_65