Fibroblast growth factor 8/FGF-8b/AIGF/HBGF-8

• Catalog number
  E21-798
• Price
  Please ask
• Size
  10ug

• Shipping_Temperature
  Ambient
• Product_State
  Lyophilized
• Formulation_Description
  Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
• Storage
  Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
• Reconstitution
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Background
  Fibroblast growth factor 8 (FGF­8) is a member of the fibroblast growth factor family. It is discovered as a growth factor essential for the androgen-­dependent growth of mouse mammary carcinoma cells. Mouse FGF­8b shares 100% aa identity with human FGF­8b. FGF­8 is widely expressed during embryogenesis, and mediates epithelial­-mesenchymal transitions. It plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. It is required for normal brain, eye, ear, limb development during embryogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.
• Alternative Names
  Fibroblast growth factor 8;Androgen-induced growth factor;Heparin-binding growth factor 8;AIGF;HBGF-8;FGF-8B
• Expression system
  E.coli
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

• Gene target
  Fibroblast   growth   factor   8/FGF-8b/AIGF/HBGF-8  
• Gene symbol
  FGF18, FGF17, FGF4, NUDT6, FGF8, FGF1, PTN, FGF3, SNORD114-8, RNU6-8
• Short name
  Fibroblast growth factor 8/FGF-8b/AIGF/HBGF-8
• Species
  Human/Mouse
• Alternative name
  Fibroblast growth factor 8/FGF-8b/AIGF/HBGF-8

Gene info

• Identity
  HGNC:3674
• Gene
  FGF18
• Long gene name
  fibroblast growth factor 18
• Synonyms
  • FGF-18
  • ZFGF5
• GenBank acession
  • AB007422
• Locus
  5q35.1
• Discovery year
  1998-12-22
• Entrez gene record
  8817
• Pubmed identfication
  • 9660775
  • 9742123
• RefSeq identity
  • NM_033649
  • NM_003862
• Classification
  • Fibroblast growth factor family
• VEGA ID
  OTTHUMG00000130464

Gene info

• Identity
  HGNC:3673
• Gene
  FGF17
• Long gene name
  fibroblast growth factor 17
• Synonyms
  • FGF-13
• GenBank acession
  • AB009249
• Locus
  8p21.3
• Discovery year
  1998-12-22
• Entrez gene record
  8822
• Pubmed identfication
  • 9514906
  • 9751161
• RefSeq identity
  • NM_003867
• Classification
  • Fibroblast growth factor family
• VEGA ID
  OTTHUMG00000097051

Gene info

• Identity
  HGNC:3682
• Gene
  FGF4
• Long gene name
  fibroblast growth factor 4
• Synonyms gene
  • HSTF1
• Synonyms gene name
  • heparin secretory transforming protein 1
• Synonyms
  • K-FGF
  • HBGF-4
  • HST
  • HST-1
  • KFGF
• Synonyms name
  • human stomach cancer, transforming factor from FGF-related oncogene
  • kaposi sarcoma oncogene
  • transforming protein KS3
• GenBank acession
  • M17446
• Locus
  11q13.3
• Discovery year
  1988-04-20
• Entrez gene record
  2249
• Pubmed identfication
  • 1611909
• RefSeq identity
  • NM_002007
• Classification
  • Fibroblast growth factor family
  • Receptor ligands
• VEGA ID
  OTTHUMG00000167887

Gene info

• Identity
  HGNC:8053
• Gene
  NUDT6
• Long gene name
  nudix hydrolase 6
• Synonyms gene name
  • nudix (nucleoside diphosphate linked moiety X)-type motif 6
• Synonyms
  • gfg-1
  • gfg
  • FGF2AS
  • FGF-AS
• GenBank acession
  • AF019632
• Locus
  4q28.1
• Discovery year
  1999-09-03
• Entrez gene record
  11162
• Pubmed identfication
  • 7984147
  • 10022609
• RefSeq identity
  • NM_007083
• Classification
  • Nudix hydrolase family
• VEGA ID
  OTTHUMG00000039507

Gene info

• Identity
  HGNC:3686
• Gene
  FGF8
• Long gene name
  fibroblast growth factor 8
• Synonyms gene name
  • fibroblast growth factor 8 (androgen-induced)
• Synonyms
  • AIGF
• Synonyms name
  • androgen-induced growth factor
• GenBank acession
  • D38752
• Locus
  10q24.32
• Discovery year
  1995-08-15
• Entrez gene record
  2253
• Pubmed identfication
  • 8595889
• RefSeq identity
  • NM_006119
  • NM_033165
• Classification
  • Fibroblast growth factor family
  • Receptor ligands
• VEGA ID
  OTTHUMG00000018940

Gene info

• Identity
  HGNC:3665
• Gene
  FGF1
• Long gene name
  fibroblast growth factor 1
• Synonyms gene
  • FGFA
• Synonyms gene name
  • fibroblast growth factor 1 (acidic)
• Synonyms
  • AFGF
  • ECGF
  • ECGFA
  • ECGFB
  • HBGF1
  • ECGF-beta
  • FGF-alpha
  • GLIO703
• Synonyms name
  • heparin-binding growth factor 1
  • endothelial cell growth factor, alpha
  • endothelial cell growth factor, beta
• GenBank acession
  • X59065
• Locus
  5q31.3
• Discovery year
  1986-01-01
• Entrez gene record
  2246
• Pubmed identfication
  • 1697263
  • 3523756
• RefSeq identity
  • NM_000800
• Classification
  • Fibroblast growth factor family
  • Receptor ligands
• VEGA ID
  OTTHUMG00000059703

Gene info

• Identity
  HGNC:9630
• Gene
  PTN
• Long gene name
  pleiotrophin
• Synonyms gene
  • NEGF1
• Synonyms gene name
  • neurite growth-promoting factor 1
• Synonyms
  • HBNF
  • HBGF8
• Synonyms name
  • heparin binding growth factor 8
• GenBank acession
  • M57399
• Locus
  7q33
• Discovery year
  1993-06-22
• Entrez gene record
  5764
• Pubmed identfication
  • 1457401
  • 1768439
• RefSeq identity
  • NM_002825
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000155709

Gene info

• Identity
  HGNC:3681
• Gene
  FGF3
• Long gene name
  fibroblast growth factor 3
• Synonyms gene
  • INT2
• Synonyms gene name
  • fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)
• Synonyms
  • HBGF-3
• Synonyms name
  • INT-2 proto-oncogene protein
  • oncogene INT2
  • V-INT2 murine mammary tumor virus integration site oncogene homolog
  • murine mammary tumor virus integration site 2, mouse
• Locus
  11q13.3
• Discovery year
  1986-01-01
• Entrez gene record
  2248
• RefSeq identity
  • NM_005247
• Classification
  • Fibroblast growth factor family
  • Receptor ligands
• VEGA ID
  OTTHUMG00000167888
• Locus Specific Databases
  • LRG_1303

Gene info

• Identity
  HGNC:32996
• Gene
  SNORD114-8
• Long gene name
  small nucleolar RNA, C/D box 114-8
• Synonyms
  • 14q(II-8)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767584
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003200.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:34285
• Gene
  RNU6-8
• Long gene name
  RNA, U6 small nuclear 8
• Synonyms
  • U6-8
• Locus
  14q12
• Discovery year
  2008-06-10
• Entrez gene record
  101954278
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_104088
• Classification
  • Small nuclear RNAs

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