Recombinant Rat Semaphorin 4D / SEMA4D / CD100 Protein (Fc tag)
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Catalog number
PKSR030237-50µg
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Price
Please ask
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Size
50µg
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Synonym
SEMA4D
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Activity
NA
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Sequence
Met1-Met712
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Fusion tag
C-Fc
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Accession
NA
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ExpressedHost
HEK293 Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
> 95 % as determined by SDS-PAGE
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Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
103.4 kDa
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AP Mol Mass
118 KDa
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Formulation
Lyophilized from sterile PBS, pH 7.4
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Background
Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.
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About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin name
Rattus norvegicus
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
SEMA4D
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Short name
Recombinant Semaphorin 4D / SEMA4D / CD100 Protein (Fc tag)
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Technique
Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Host
Rat
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Label
Fc Tag
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Species
Rat, Rats
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Alternative name
Rec. Rat Semaphorin 4D / sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D / CD100 Protein (fragment c detection labelled)
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Alternative technique
rec
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Alternative to gene target
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D, C9orf164 and CD100 and coll-4 and M-sema-G and SEMAJ, SEMA4D and IDBG-75424 and ENSG00000187764 and 10507, semaphorin receptor binding, Extracellular, Sema4d and IDBG-152500 and ENSMUSG00000021451 and 20354, SEMA4D and IDBG-637043 and ENSBTAG00000001941 and 785942
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Gene info
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Identity
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Gene
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Long gene name
semaphorin 4D
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Synonyms gene
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Synonyms gene name
- chromosome 9 open reading frame 164
- sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1999-06-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Immunoglobulin like domain containing
- Semaphorins
- CD molecules
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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