Recombinant Rat CD10 / Neprilysin / MME Protein (His tag) 20µg
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Catalog numberPKSR030257-20µg
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Price:
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Size20µg
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SynonymMME
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ActivityNA
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SequenceTyr52-Trp750
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Fusion tagN-His
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AccessionP07861
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ExpressedHostHEK293 Cells
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ShippingIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity> 95 % as determined by SDS-PAGE
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Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and StorageSamples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass82.5 kDa
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AP Mol Mass93 KDa
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FormulationLyophilized from sterile PBS, pH 7.4
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BackgroundThe cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 10 (CD10), also known as Neprilysin and neutral endopeptidase, is a member of the CD system. CD10 is a zinc-dependent metalloprotease enzyme that had function to degrade a number of small secreted peptides such as the amyloid beta peptide. It exist as a membrane-bound protein and have high concentration in kidney and lung tissues. Mutations in the CD10 gene can induce the familial forms of Alzheimer's disease, providing strong evidence for the protein's association with the Alzheimer's disease process. CD10 is also associated with other biochemical processes.
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Conjugationhistidine
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AboutRats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin nameRattus norvegicus
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolMME, MME-AS1
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Short nameRecombinant CD10 / Neprilysin / MME Protein (His tag) 20µg
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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HostRat
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LabelHis
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SpeciesRat, Rats
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Alternative nameRec. Rat CD10 / Neprilysin / MME Protein (histidine detection labelled) 20µg
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene namemembrane metalloendopeptidase
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Synonyms
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Synonyms name
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Locus
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Discovery year1989-05-15
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Entrez gene record
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RefSeq identity
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Classification
- M13 metallopeptidases
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameMME antisense RNA 1
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Synonyms gene name
- MME antisense RNA 1 (non-protein coding)
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Locus
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Discovery year2011-07-27
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Classification
- Antisense RNAs
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data