Recombinant Mouse PGLYRP1 / PGRP-S Protein (His tag)

• Catalog number
  PKSM040857-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  Pglyrp;PGRP;PGRP-S;Tag7;Tasg7;Tnfsf3l
• Activity
  NA
• Sequence
  Met 1-Glu 182
• Fusion tag
  C-His
• Accession
  O88593
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 95 % as determined by SDS-PAGE
• Endotoxin
  < 1.0 EU per μg of the protein as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  20.2 kDa
• AP Mol Mass
  18-21 kDa
• Formulation
  Lyophilized from PBS, pH 7.4, 10 % glycerol
• Background
  Peptidoglycan recognition protein 1, also known as Peptidoglycan recognition protein short, PGRP-S, PGLYRP1, PGLYRP, PGRP and TNFSF3L, is a secreted protein which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. PGLYRP1 / PGLYRP is highly expressed in bone marrow. It is weakly expressed in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils. PGLYRP1 / PGLYRP is a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. It has bactericidal activity towards Gram-positive bacteria. PGLYRP1 / PGLYRP may kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. It binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Peptidoglycan recognition proteins ( PGRPs or PGLYRPs ) are innate immunity proteins that are conserved from insects to mammals, recognize bacterial peptidoglycan, and function in antibacterial immunity and inflammation. Mammals have four PGRPs: PGLYRP1, PGLYRP2, PGLYRP3, and PGLYRP4. They are secreted proteins expressed in polymorphonuclear leukocytes ( PGLYRP1 ), liver ( PGLYRP2 ), or on body surfaces, mucous membranes, and in secretions (saliva, sweat) (PGLYRP3 and PGLYRP4). All PGRPs recognize bacterial peptidoglycan. The PGRPs likely play a role both in antibacterial defenses and several inflammatory diseases. They modulate local inflammatory responses in tissues (such as arthritic joints) and there is evidence for association of PGRPs with inflammatory diseases, such as psoriasis.
• Technical data
• Conjugation
  histidine
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  PGLYRP1   PGRP-S   Protein   His   tag  
• Gene symbol
  PGLYRP1, B3GAT2, PGLYRP3, CTSL3P, HLA-S, STRN3, PGLYRP4, DIABLO, H2BC19P, MAG
• Short name
  Recombinant Mouse PGLYRP1 / PGRP-S Protein (His tag)
• Technique
  Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Host
  mouse
• Label
  His
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse PGLYRP1 / PGRP-S Protein (histidine detection labelled)
• Alternative technique
  rec, murine

Gene info

• Identity
  HGNC:8904
• Gene
  PGLYRP1
• Long gene name
  peptidoglycan recognition protein 1
• Synonyms gene
  • TNFSF3L
  • PGLYRP
• Synonyms gene name
  • peptidoglycan recognition protein
• Synonyms
  • TAG7
  • PGRP
  • PGRP-S
  • PGRPS
• GenBank acession
  • AF076483
• Locus
  19q13.32
• Discovery year
  1999-01-15
• Entrez gene record
  8993
• Pubmed identfication
  • 9707603
  • 12669421
• RefSeq identity
  • NM_005091
• Classification
  • Peptidoglycan recognition proteins
• VEGA ID
  OTTHUMG00000182489

Gene info

• Identity
  HGNC:922
• Gene
  B3GAT2
• Long gene name
  beta-1,3-glucuronyltransferase 2
• Synonyms
  • GlcAT-S
• Synonyms name
  • glucuronosyltransferase S
  • galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2
• GenBank acession
  • AB075843
• Locus
  6q13
• Discovery year
  2000-01-07
• Entrez gene record
  135152
• Pubmed identfication
  • 12383500
• RefSeq identity
  • NM_080742
• Classification
  • Beta-1,3-glucuronyltransferases
• VEGA ID
  OTTHUMG00000014997

Gene info

• Identity
  HGNC:30014
• Gene
  PGLYRP3
• Long gene name
  peptidoglycan recognition protein 3
• Synonyms
  • PGRPIA
  • PGLYRPIalpha
  • PGRP-Ialpha
• Synonyms name
  • peptidoglycan recognition protein I alpha precursor
• GenBank acession
  • AY035376
• Locus
  1q21.3
• Discovery year
  2004-03-17
• Entrez gene record
  114771
• Pubmed identfication
  • 11461926
• RefSeq identity
  • NM_052891
• Classification
  • Peptidoglycan recognition proteins
• VEGA ID
  OTTHUMG00000014044

Gene info

• Identity
  HGNC:33132
• Gene
  CTSL3P
• Long gene name
  cathepsin L family member 3, pseudogene
• Synonyms gene
  • CTSL3
• Synonyms gene name
  • cathepsin L family member 3
• Synonyms
  • HCTSL-s
• GenBank acession
  • AJ851862
• Locus
  9q21.33
• Discovery year
  2007-04-27
• Entrez gene record
  392360
• Pubmed identfication
  • 19663681
• RefSeq identity
  • NR_027917
• VEGA ID
  OTTHUMG00000020152

Gene info

• Identity
  HGNC:19395
• Gene
  HLA-S
• Long gene name
  major histocompatibility complex, class I, S (pseudogene)
• Synonyms
  • HLA-17
• GenBank acession
  • M96339
• Locus
  6p21.33
• Discovery year
  2002-10-23
• Entrez gene record
  267015
• Pubmed identfication
  • 10452889
  • 1517563
• RefSeq identity
  • NG_009941
• Classification
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031178
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:15720
• Gene
  STRN3
• Long gene name
  striatin 3
• Synonyms gene name
  • striatin, calmodulin binding protein 3
• Synonyms
  • SG2NA
  • PPP2R6B
  • S/G2NA
• Synonyms name
  • cell cycle S/G2 nuclear autoantigen
  • protein phosphatase 2 regulatory subunit B'''beta
• Locus
  14q12
• Discovery year
  2002-07-22
• Entrez gene record
  29966
• Pubmed identfication
  • 7864889
  • 10681496
• RefSeq identity
  • NM_014574
• Classification
  • WD repeat domain containing
  • STRIPAK complex
  • Protein phosphatase 2 regulatory subunits
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000140201

Gene info

• Identity
  HGNC:30015
• Gene
  PGLYRP4
• Long gene name
  peptidoglycan recognition protein 4
• Synonyms
  • SBBI67
  • PGRPIB
  • PGLYRPIbeta
  • PGRP-Ibeta
• Synonyms name
  • peptidoglycan recognition protein I beta precursor
• GenBank acession
  • AF242518
• Locus
  1q21.3
• Discovery year
  2004-03-17
• Entrez gene record
  57115
• Pubmed identfication
  • 11461926
• RefSeq identity
  • NM_020393
• Classification
  • Peptidoglycan recognition proteins
• VEGA ID
  OTTHUMG00000037057

Gene info

• Identity
  HGNC:21528
• Gene
  DIABLO
• Long gene name
  diablo IAP-binding mitochondrial protein
• Synonyms gene name
  • diablo, IAP-binding mitochondrial protein
• Synonyms
  • SMAC
  • DIABLO-S
  • FLJ25049
  • FLJ10537
  • DFNA64
• Synonyms name
  • second mitochondria-derived activator of caspase
• GenBank acession
  • AF262240
• Locus
  12q24.31
• Discovery year
  2003-10-27
• Entrez gene record
  56616
• Pubmed identfication
  • 12749848
  • 17237824
  • 21722859
• RefSeq identity
  • NM_019887
• VEGA ID
  OTTHUMG00000157014

Gene info

• Identity
  HGNC:20517
• Gene
  H2BC19P
• Long gene name
  H2B clustered histone 19, pseudogene
• Synonyms gene
  • H2BFO
  • HIST2H2BD
• Synonyms gene name
  • histone 2, H2bd
  • H2B histone family, member O
  • histone cluster 2, H2bd (pseudogene)
  • histone cluster 2 H2B family member d (pseudogene)
• Synonyms
  • H2B/s
  • H2B/o
• GenBank acession
  • AY131978
• Locus
  1q21.2
• Discovery year
  2003-02-20
• Entrez gene record
  337874
• Pubmed identfication
  • 12408966
  • 15527963
• RefSeq identity
  • NG_001226
• Classification
  • H2B histones
• VEGA ID
  OTTHUMG00000035827

Gene info

• Identity
  HGNC:6783
• Gene
  MAG
• Long gene name
  myelin associated glycoprotein
• Synonyms gene
  • GMA
• Synonyms
  • SIGLEC4A
  • SIGLEC-4A
  • S-MAG
• Synonyms name
  • sialic acid binding Ig-like lectin 4A
• GenBank acession
  • M29273
• Locus
  19q13.1
• Discovery year
  2001-06-22
• Entrez gene record
  4099
• Pubmed identfication
  • 2476987
  • 8432525
• RefSeq identity
  • NM_080600
• Classification
  • C2-set domain containing
  • I-set domain containing
  • Sialic acid binding Ig like lectins
• VEGA ID
  OTTHUMG00000183296

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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