Recombinant Mouse Mannose Binding Lectin 2/MBL-2/MBP-C Protein 50µg

Catalog number

PKSM041108-50µg
Price

Please ask
Size

50µg

Activity

NA
Synonym

Mannose binding lectin (C); isoform CRA_b; Mannose-binding protein C; Mbl2; MBL-2; Mannose Binding Lectin 2
Sequence

Glu19-Asp244
Fusion tag

NA
Accession

Q3UEK1
Expressed Host

Human Cells
Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Purity

＞95% as determined by reducing SDS-PAGE.
Stability and Storage

Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
Mol Mass

24.0 kDa
AP Mol Mass

28 kDa
Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Background

Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum, it further polymerizes forming dimers to octamers. The degree of serum polymerization is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria, fungi, protozoa and viruses and acts as an acute-phase plasma protein (APP) during infection and inflammation. MBL activates the lectin-complement pathway, promotes opsonophagocytosis and modulates inflammation.
Technical data
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Mannose Binding Lectin 2/MBL-2/MBP-C Protein 50µg
Gene symbol

MBL2, MBP, HIVEP2, ERVFC1-1, PRG2, SMC4, ENO1, BIRC2, MYB, PCK1
Short name

Recombinant Mouse Mannose Binding Lectin 2/MBL-2/MBP-C Protein 50µg
Technique

Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

mouse
Label

mbp
Species

Mouse, Mouses
Alternative name

Rec. Mouse Mannose Binding Lectin 2/MBL-2/MBP-C Protein 50µg
Alternative technique

rec, murine

Gene info

Identity

HGNC:6922
Gene

MBL2
Long gene name

mannose binding lectin 2
Synonyms gene
- MBL
Synonyms gene name
- mannose-binding lectin (protein C) 2, soluble (opsonic defect)
- mannose-binding lectin (protein C) 2, soluble
Synonyms
- COLEC1
GenBank acession
- AF360991
Locus

10q21.1
Discovery year

1990-05-25
Entrez gene record

4153
Pubmed identfication
- 1675710
- 1672848
RefSeq identity
- NM_000242
Classification
- Complement system activation components
- Collectins
VEGA ID

OTTHUMG00000150270
Locus Specific Databases
- LRG_154

Gene info

Identity

HGNC:6925
Gene

MBP
Long gene name

myelin basic protein
Locus

18q23
Discovery year

1986-01-01
Entrez gene record

4155
Pubmed identfication
- 2425357
RefSeq identity
- NM_001025081
VEGA ID

OTTHUMG00000132874

Gene info

Identity

HGNC:4921
Gene

HIVEP2
Long gene name

HIVEP zinc finger 2
Synonyms gene name
- human immunodeficiency virus type I enhancer-binding protein 2
- human immunodeficiency virus type I enhancer binding protein 2
Synonyms
- MBP-2
- HIV-EP2
- MIBP1
- ZAS2
- Schnurri-2
- ZNF40B
Synonyms name
- c-myc intron binding protein 1
GenBank acession
- M60119
Locus

6q24.2
Discovery year

1992-10-21
Entrez gene record

3097
Pubmed identfication
- 1733857
- 2022670
Classification
- Zinc fingers C2H2-type
VEGA ID

OTTHUMG00000015713

Gene info

Identity

HGNC:38137
Gene

ERVFC1-1
Long gene name

endogenous retrovirus group FC1 member 1, envelope
Synonyms gene name
- endogenous retrovirus group FC1, member 1
- endogenous retrovirus group FC1 member 1
Synonyms
Synonyms name
- HERV-F(c)2_7q36.2 provirus ancestral Env polyprotein
GenBank acession
- AK124285
Locus

7q36.2
Discovery year

2011-05-05
Entrez gene record

346547
Pubmed identfication
- 12970426
- 21542922
Classification
- Envelope ERV derived genes

Gene info

Identity

HGNC:9362
Gene

PRG2
Long gene name

proteoglycan 2, pro eosinophil major basic protein
Synonyms gene name
- proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
Synonyms
- MBP
- BMPG
- proMBP
Synonyms name
- eosinophil major basic protein
GenBank acession
- BC005929
Locus

11q12.1
Discovery year

1993-09-29
Entrez gene record

5553
Pubmed identfication
- 1565101
RefSeq identity
- NM_002728
Classification
- C-type lectin domain containing
VEGA ID

OTTHUMG00000167027

Gene info

Identity

HGNC:14013
Gene

SMC4
Long gene name

structural maintenance of chromosomes 4
Synonyms gene
- SMC4L1
Synonyms gene name
- SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
- SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
Synonyms
- hCAP-C
- CAP-C
GenBank acession
- AF092564
Locus

3q25.33
Discovery year

2001-02-22
Entrez gene record

10051
Pubmed identfication
- 9789013
- 10319587
Classification
- Structural maintenance of chromosomes proteins
- Condensin I subunits
- Condensin II subunits
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000159006

Gene info

Identity

HGNC:3350
Gene

ENO1
Long gene name

enolase 1
Synonyms gene
- ENO1L1
- MPB1
Synonyms gene name
- enolase 1, (alpha)
Synonyms
- PPH
- MBP-1
Synonyms name
- alpha-enolase
GenBank acession
- BC022545
Locus

1p36.23
Discovery year

1989-04-21
Entrez gene record

2023
Pubmed identfication
- 9653645
- 9691177
RefSeq identity
- NM_001428
Classification
- Enolases
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000001773
Locus Specific Databases
- LRG_1165

Gene info

Identity

HGNC:590
Gene

BIRC2
Long gene name

baculoviral IAP repeat containing 2
Synonyms gene
- API1
Synonyms gene name
- baculoviral IAP repeat-containing 2
Synonyms
- cIAP1
- hiap-2
- MIHB
- RNF48
- c-IAP1
Synonyms name
- NFR2-TRAF signalling complex protein
- apoptosis inhibitor 1
GenBank acession
- L49431
Locus

11q22.2
Discovery year

1998-06-10
Entrez gene record

329
Pubmed identfication
- 8552191
- 8548810
RefSeq identity
- NM_001166
Classification
- Baculoviral IAP repeat containing
- Ring finger proteins
- Caspase recruitment domain containing
VEGA ID

OTTHUMG00000167325

Gene info

Identity

HGNC:7545
Gene

MYB
Long gene name

MYB proto-oncogene, transcription factor
Synonyms gene name
- v-myb avian myeloblastosis viral oncogene homolog
Synonyms
- c-myb
Locus

6q23.3
Discovery year

2001-06-22
Entrez gene record

4602
Pubmed identfication
- 17599807
Classification
- Myb/SANT domain containing
VEGA ID

OTTHUMG00000015629
Locus Specific Databases
- The Globin Gene Server

Gene info

Identity

HGNC:8724
Gene

PCK1
Long gene name

phosphoenolpyruvate carboxykinase 1
Synonyms gene name
- phosphoenolpyruvate carboxykinase 1 (soluble)
Synonyms
- PEPCK-C
Locus

20q13.31
Discovery year

1990-09-10
Entrez gene record

5105
Pubmed identfication
- 1492743
VEGA ID

OTTHUMG00000032825

MeSH Data

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Recombinant Mouse Mannose Binding Lectin 2/MBL-2/MBP-C Protein 50µg

Gene info

Gene info

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Gene info

Gene info

Gene info

Gene info

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Gene info

Gene info

MeSH Data

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