Recombinant Mouse IAP/OA3/CD47 Protein(C-Fc) 50µg
-
Catalog number
PKSM041043-50µg
-
Price
Please ask
-
Size
50µg
-
-
Activity
NA
-
Synonym
Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6
-
Sequence
Gln19-Pro158
-
Fusion tag
C-Fc
-
Accession
Q61735-2
-
Expressed Host
Human Cells
-
Shipping
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
-
Purity
＞95% as determined by reducing SDS-PAGE.
-
Stability and Storage
Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
-
Mol Mass
42.8 kDa
-
AP Mol Mass
60-90 kDa
-
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
-
Background
CD47, also known as Integrin-Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral membrane protein that consists of a extracellular domain (ECD) with a single Ig-like domain, five membrane-spanning regions with short intervening loops, and C-terminal cytoplasmic tail. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It plays an important role in memory formation and synaptic plasticity in the hippocampus. As a receptor for SIRPA, it binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cellcell adhesion, it enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. It may play a role in membrane transport and/or integrin dependent signal transduction. It also prevents premature elimination of red blood cells.
-
-
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin name
Mus musculus
-
Source
Recombinants or rec. proteins
-
Group
recombinants
-
Gene target
-
Gene symbol
CD47, ALPI, IAPP, MAGT1, BIRC7
-
Short name
Recombinant Mouse IAP/OA3/CD47 Protein(C-Fc) 50µg
-
Technique
Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
Host
mouse
-
Species
Mouse, Mouses
-
Alternative name
Rec. Mouse IAP/OA3/CD47 molecule Protein(C-fragment c) 50µg
-
Alternative technique
rec, murine
-
Alternative to gene target
CD47 molecule, IAP and MER6 and OA3, CD47 and IDBG-48744 and ENSG00000196776 and 961, thrombospondin receptor activity, Plasma membranes, Cd47 and IDBG-165137 and ENSMUSG00000055447 and 16423, CD47 and IDBG-631689 and ENSBTAG00000003585 and 282661
-
Gene info
-
Identity
-
Gene
-
Long gene name
CD47 molecule
-
Synonyms gene
-
Synonyms gene name
- CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year
1994-12-12
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- CD molecules
- Ig-like cell adhesion molecule family
- Immunoglobulin like domain containing
-
VEGA ID
Gene info
Gene info
Gene info
-
Identity
-
Gene
-
Long gene name
magnesium transporter 1
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year
2008-01-18
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Oligosaccharyltransferase complex subunits
- Solute carriers
-
VEGA ID
-
Locus Specific Databases
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
-
Tree numbers
- E01.370.225.500.195.107.595.500.150
- E01.370.225.625.107.595.500.150
- E05.200.500.195.107.595.500.150
- E05.200.625.107.595.500.150
- E05.242.195.107.595.500.150
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
