Recombinant Mouse Granzyme B(G,H)/GZMB Protein(C-6His) 50µg

• Catalog number
  PKSM041035-50µg
• Price
  Please ask
• Size
  50µg

• Activity
  NA
• Synonym
  Granzyme B(G;H);CTLA-1;Cytotoxic cell protease 1;CCP1;Fragmentin-2;Gzmb;Ctla-1; Ctla1
• Sequence
  Gly19-Ser247
• Fusion tag
  C-6His
• Accession
  P04187
• Expressed Host
  Human Cells
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞85% as determined by reducing SDS-PAGE.
• Stability and Storage
  Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
• Mol Mass
  26.5 kDa
• AP Mol Mass
  35kDa
• Formulation
  Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
• Background
  Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
• Technical data
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Granzyme   GZMB   Protein   C-6His   50µg  
• Gene symbol
  GZMB
• Short name
  Recombinant Mouse Granzyme B(G H)/GZMB Protein(C-6His) 50µg
• Technique
  Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  mouse
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse Granzyme B(G,H)/granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) Protein(C-6His) 50µg
• Alternative technique
  rec, murine
• Alternative to gene target
  granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), CCPI and CGL-1 and CGL1 and CSP-B and CSPB and CTLA1 and CTSGL1 and HLP and SECT, GZMB and IDBG-4054 and ENSG00000100453 and 3002, serine-type peptidase activity, nuclei, BT.19365 and IDBG-632083 and ENSBTAG00000010057 and 508646

Gene info

• Identity
  HGNC:4709
• Gene
  GZMB
• Long gene name
  granzyme B
• Synonyms gene
  • CTLA1
  • CSPB
• Synonyms gene name
  • granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
• Synonyms
  • CCPI
  • CGL-1
  • CSP-B
  • CGL1
  • CTSGL1
  • HLP
  • SECT
• Synonyms name
  • fragmentin 2
  • cytotoxic serine protease B
  • cathepsin G-like 1
  • T-cell serine protease 1-3E
  • granzyme 2
  • cytotoxic T-lymphocyte-associated serine esterase 1
• GenBank acession
  • BC030195
• Locus
  14q12
• Discovery year
  1989-05-12
• Entrez gene record
  3002
• Pubmed identfication
  • 2323780
• RefSeq identity
  • NM_004131
• Classification
  • Granule associated serine proteases of immune defence
• VEGA ID
  OTTHUMG00000029369

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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