Recombinant Mouse CXADR / CAR Protein
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Catalog number
PKSM040909-20µg
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Price
Please ask
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Size
20µg
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Synonym
2610206D03Rik;AU016810;AW553441;CAR;MCAR;MCVADR
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Activity
NA
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Sequence
Met 1-Gly 237
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Fusion tag
NA
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Accession
NP_001020363.1
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Expressed Host
HEK293 Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
> 95 % as determined by SDS-PAGE
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Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
25 kDa
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AP Mol Mass
30 kDa
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Formulation
Lyophilized from sterile PBS, pH 7.4
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Background
CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 107 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 90% sequence identity with the corresponding regions of rat, human CXADR.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
CXADR, CXADRP1, NR1I3, SPG7
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Short name
Recombinant Mouse CXADR / CAR Protein
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Technique
Recombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
mouse
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Species
Mouse, Mouses
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Alternative name
Rec. Mouse coxsackie virus and adenovirus receptor / CAR Protein
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Alternative technique
rec, murine
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Alternative to gene target
coxsackie virus and adenovirus receptor, CAR and CAR4/6 and HCAR, CXADR and IDBG-854 and ENSG00000154639 and 1525, connexin binding, nuclei, Gm1123 and IDBG-192613 and ENSMUSG00000044860 and 382097, CXADR and IDBG-630474 and ENSBTAG00000004869 and 281733
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Gene info
Gene info
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Identity
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Gene
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Long gene name
CXADR pseudogene 1
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Synonyms gene name
- coxsackie virus and adenovirus receptor pseudogene 1
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Synonyms
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Locus
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Discovery year
2008-01-31
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Entrez gene record
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VEGA ID
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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