Recombinant Human Tropomyosin α-3 Chain/TPM3 Protein 50µg

• Catalog number
  PKSH033151-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  Tropomyosin Alpha-3 Chain; Gamma-Tropomyosin; Tropomyosin-3; Tropomyosin-5; hTM5; TPM3
• Activity
  NA
• Sequence
  Met1-Met248
• Fusion tag
  NA
• Accession
  P06753-2
• Expressed Host
  E.coli
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞90% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
• Mol Mass
  29.0 kDa
• AP Mol Mass
  32 kDa
• Formulation
  Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
• Reconstitution
  Please refer to it for detailed information.
• Background
  Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the calcium dependent regulation of vertebrate striated muscle contraction. Defects in TPM3 are the cause of thyroid papillary carcinoma. Mutations in the TPM3 gene cause autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are linked with cancer.
• Product URL
• PDF URL
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Tropomyosin   α-3   Chain/TPM3   Protein   50µg  
• Gene symbol
  TPM3
• Short name
  Recombinant Tropomyosin α-3 Chain/TPM3 Protein 50µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Tropomyosin α-3 epitope/TPM3 Protein 50µg
• Alternative technique
  rec

Gene info

• Identity
  HGNC:12012
• Gene
  TPM3
• Long gene name
  tropomyosin 3
• Synonyms gene
  • NEM1
• Synonyms
  • TRK
• GenBank acession
  • BC008425
• Locus
  1q21.3
• Discovery year
  1991-07-18
• Entrez gene record
  7170
• Pubmed identfication
  • 1829807
  • 25369766
• RefSeq identity
  • NM_152263
• Classification
  • Tropomyosins
• VEGA ID
  OTTHUMG00000035853
• Locus Specific Databases
  • Leiden Muscular Dystrophy pages
  • LRG_681

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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