Recombinant Human Transcriptional Repressor Protein YY1 Protein(C-6His)

• Catalog number
  PKSH033137-10µg
• Price
  Please ask
• Size
  10µg

• Synonym
  Transcriptional repressor protein YY1;Delta transcription factor;INO80 complex subunit S;NF-E1;Yin and yang 1;INO80S
• Activity
  NA
• Sequence
  Val221-Gly321
• Fusion tag
  C-6His
• Accession
  P25490
• Expressed Host
  E.coli
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
• Mol Mass
  12.6 kDa
• AP Mol Mass
  17 kDa
• Formulation
  Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Background
  Transcriptional repressor protein YY1（YY1）contains 4 C2H2-type zinc fingers and belongs to the YY transcription factor family. Multifunctional transcription factor exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. The effect on transcription regulation of the protein is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repression, indirect activation or repression via cofactor recruitment, or activation or repression by disruption of binding sites or conformational DNA changes. Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression.
• Technical data
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Transcriptional   Repressor   Protein   YY1   Protein   C-6His  
• Gene symbol
  YY1
• Short name
  Recombinant Transcriptional Repressor Protein YY1 Protein(C-6His)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Transcriptional Repressor Protein YY1 Protein(C-6His)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:12856
• Gene
  YY1
• Long gene name
  YY1 transcription factor
• Synonyms
  • NF-E1
  • DELTA
  • UCRBP
  • YIN-YANG-1
  • INO80S
• Synonyms name
  • INO80 complex subunit S
  • Yin and Yang 1 protein
• GenBank acession
  • BC020324
• Locus
  14q32.2
• Discovery year
  1993-09-17
• Entrez gene record
  7528
• Pubmed identfication
  • 1655281
  • 7912122
• RefSeq identity
  • NM_003403
• Classification
  • INO80 complex
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000150479

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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