Recombinant Human SPOCK1 / Testican 1 Protein (aa 21-429, His tag)
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Catalog number
PKSH031498-20µg
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Price
Please ask
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Size
20µg
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Synonym
SPOCK;TESTICAN;TIC1
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Activity
NA
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Sequence
Met 1-Trp439
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Fusion tag
C-His
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Accession
Q08629
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Expressed Host
Baculovirus-Insect Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
>85 % as determined by SDS-PAGE
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Endotoxin
<1.0 EU per µg as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
48.4 kDa
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AP Mol Mass
53 kDa
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Formulation
Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 7.4
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Background
Osteonectin, also known as SPOCK1, is an extracellular heparan/chondroitin sulfate proteoglycan. Members of this family are known as testicans, also called SPOCKs. They are characterized structurally by an N-terminal testican-specific domain, a follistatin-like region, a calcium-binding domain, a thyroglobulin-like domain, and an acidic C-terminal domain with two putative glycosaminoglycan attachment sites. SPOCKs are enriched in brain and have been shown to regulate neuronal attachment and outgrowth. They contain inhibitory regions in several domains targeted to different classes of protease, and in some cases may act as protease inhibitors. Osteonectin contains 1 Kazal-like domain and 1 thyroglobulin type-1 domain. Up to now, little is known about osteonectin’s function. It may play a role in cell-cell and cell-matrix interactions. Osteonectin also may contribute to various neuronal mechanisms in the central nervous system.
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Conjugation
histidine
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
SNORD100, PIRC105, SNORD115-21, HTOR, SNORD116-21, SNORD114-21
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Short name
Recombinant SPOCK1 / Testican 1 Protein (aa 21-429, His tag)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Label
His
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Species
Human, Humans
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Alternative name
Rec. H. sapiens secreted protein, acidic, cysteine-rich (osteonectin)/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 / Testican 1 Protein (aa 21-429, histidine detection labelled)
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Alternative technique
rec
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Alternative to gene target
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1, SPOCK and TESTICAN and TIC1, SPOCK1 and IDBG-46103 and ENSG00000152377 and 6695, metalloendopeptidase inhibitor activity, Extracellular, Spock1 and IDBG-157690 and ENSMUSG00000056222 and 20745, SPOCK1 and IDBG-645860 and ENSBTAG00000003502 and 511211
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Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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