Recombinant Human Serpin A6 /Transcortin Protein(C-6His)

  • Catalog number
    PKSH033035-10µg
  • Price
    Please ask
  • Size
    10µg
  • Synonym
    Corticosteroid-Binding Globulin; CBG; Serpin A6; Transcortin; SERPINA6; CBG
  • Activity
    NA
  • Sequence
    Met23-Val405
  • Fusion tag
    C-6His
  • Accession
    P08185
  • Expressed Host
    Human cells
  • Shipping
    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
  • Purity
    >95% as determined by reducing SDS-PAGE.
  • Endotoxin
    <1.0 EU per µg as determined by LAL test.
  • Stability and Storage
    Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
  • Mol Mass
    43.7 kDa
  • AP Mol Mass
    58 kDa
  • Formulation
    Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
  • Background
    Serpin Peptidase Inhibitor, Clade A, Member 6 (SerpinA6) belongs to the Serine Protease Inhibitors superfamily. SerpinA6 is synthesized in liver and has also been identified in a number of glycocorticoid responsive cells. SerpinA6 has an alpha-globulin protein with corticosteroid-binding properties. It is the major transport protein for glucocorticoids and progestins in the blood of most vertebrates. Defects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency which is an extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Short name
    Recombinant Serpin A6 /Transcortin Protein(C-6His)
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    Rec. H. sapiens Serpin A6 /Transcortin Protein(C-6His)
  • Alternative technique
    rec
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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