Recombinant Human PTH / parathyroid hormone Protein (aa 32-65, GST tag) 100µg

  • Catalog number
    PKSH030707-100µg
  • Price
    Please ask
  • Size
    100µg
  • Synonym
    PTH;PTH1
  • Activity
    NA
  • Sequence
    Ser 32-Phe 65
  • Fusion tag
    N-GST
  • Accession
    P05062
  • Expressed Host
    E. coli
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    >96 % as determined by SDS-PAGE
  • Endotoxin
    Please contact us for more information.
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    31 kDa
  • AP Mol Mass
    30 kDa
  • Formulation
    Lyophilized from sterile PBS, pH 7.5
  • Reconstitution
    Please refer to it for detailed information.
  • Background
    Parathyroid hormone (PTH), parathormone or parathyrin, is secreted by the chief cells of the parathyroid glands as a polypeptide. PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Parathyroid hormone (PTH) has been proved to play a pivotal role in maintaining myocardial contractility as well as effective natriuresis, and possible pathogenic mechanisms contributing to heart failure secondary to hypocalcemia and hypoparathyroidism. With the increased population of preosteoblastic lineages and the osteoblastic activation, Parathyroid hormone (PTH) drives anabolism in bone. Experiments have recently reported that PTH affects bone cells in a dual pathway - mediating osteoblastic (preosteoblastic) activities or osteocytic synthesis of sclerostin. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps.
  • Description
    Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    PTH   parathyroid   hormone   Protein   32-65   GST   tag   100µg  
  • Gene symbol
    PTH, IGLVIV-65, IGHVII-65-1, MGST3, IGHV3-65, IGKV1D-32, SNORD115-32, RNU6-65P, PPP1R1B, NDUFAF1
  • Short name
    Recombinant PTH / parathyroid hormone Protein (aa 32-65, GST tag) 100µg
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Label
    tag
  • Species
    Human, Humans
  • Alternative name
    Rec. H. sapiens parathyroid hormone / parathyroid hormone Protein (aa 32-65, GST detection labelled) 100µg
  • Alternative technique
    rec
  • Alternative to gene target
    parathyroid hormone, PTH1, PTH and IDBG-32891 and ENSG00000152266 and 5741, peptide hormone receptor binding, Extracellular, Pth and IDBG-207092 and ENSMUSG00000059077 and 19226, PTH and IDBG-632953 and ENSBTAG00000019080 and 280903
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin lambda variable (IV)-65 (pseudogene)
  • Synonyms gene name
    • immunoglobulin lambda variable (IV)-65
    • immunoglobulin lambda variable (IV)-65 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-05-08
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin lambda locus at 22q11.2
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable (II)-65-1 (pseudogene)
  • Synonyms gene name
    • immunoglobulin heavy variable (II)-65-1
    • immunoglobulin heavy variable (II)-65-1 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-17
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin heavy variable 3-65 (pseudogene)
  • Synonyms gene name
    • immunoglobulin heavy variable 3-65
    • immunoglobulin heavy variable 3-65 pseudogene
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-04
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    immunoglobulin kappa variable 1D-32 (pseudogene)
  • Synonyms gene name
    • immunoglobulin kappa variable 1D-32
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-18
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Immunoglobulin kappa locus at 2p11.2
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    RNA, U6 small nuclear 65, pseudogene
  • Synonyms gene
  • Synonyms gene name
    • RNA, U6 small nuclear 65
  • Locus
  • Discovery year
    2011-08-08
  • Entrez gene record
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    NADH:ubiquinone oxidoreductase complex assembly factor 1
  • Synonyms gene name
    • NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2004-02-02
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Mitochondrial complex I assembly complex
    • Mitochondrial respiratory chain complex assembly factors
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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