Recombinant Human PDGF-B Protein (His Tag) 200µg

• Catalog number
  PKSH030442-200µg
• Price
  Please ask
• Size
  200µg

• Synonym
  c-sis;IBGC5;PDGF-2;PDGF2;SIS;SSV
• Activity
  Measured by its binding ability in a functional ELISA.2.Immobilized human PDGFB at 10μg/mL (100μL/well) can bind human PDGFRβ-Fch, the EC50 of human PDGFRβ-Fch is 0.05-0.2 μg/mL.
• Sequence
  Ser82-Thr190
• Fusion tag
  N-His
• Accession
  NP_148937.1
• Expressed Host
  Yeast
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞95 % as determined by SDS-PAGE.
• Endotoxin
  Please contact us for more information.
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  14.3 kDa
• AP Mol Mass
  14.3 kDa
• Formulation
  Lyophilized from sterile PBS, 25 % Glycerol, pH 7.4
• Reconstitution
  Please refer to it for detailed information.
• Background
  Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
• Product URL
• PDF URL
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  PDGF-B   Protein   His   Tag   200µg  
• Gene symbol
  PDGFB, PDGFA, SNRPB, ORM2, ERAL1, OR1B1, SPIB, EXPH5, HLA-B, RELB
• Short name
  Recombinant PDGF-B Protein (His Tag) 200µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens PDGF-B Protein (histidine detection labelled) 200µg
• Alternative technique
  rec

Gene info

• Identity
  HGNC:8800
• Gene
  PDGFB
• Long gene name
  platelet derived growth factor subunit B
• Synonyms gene
  • SIS
• Synonyms gene name
  • platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
  • platelet-derived growth factor beta polypeptide
• Synonyms
  • SSV
• Synonyms name
  • oncogene SIS
  • becaplermin
• Locus
  22q13.1
• Discovery year
  2001-06-22
• Entrez gene record
  5155
• Pubmed identfication
  • 2991848
  • 1661670
• RefSeq identity
  • NM_002608
• VEGA ID
  OTTHUMG00000151029

Gene info

• Identity
  HGNC:8799
• Gene
  PDGFA
• Long gene name
  platelet derived growth factor subunit A
• Synonyms gene name
  • platelet-derived growth factor alpha polypeptide
• Synonyms
  • PDGF1
  • PDGF-A
• Synonyms name
  • PDGF A-chain
  • platelet-derived growth factor alpha chain
• Locus
  7p22.3
• Discovery year
  1986-01-01
• Entrez gene record
  5154
• Pubmed identfication
  • 1505216
  • 2536956
• VEGA ID
  OTTHUMG00000151412

Gene info

• Identity
  HGNC:11153
• Gene
  SNRPB
• Long gene name
  small nuclear ribonucleoprotein polypeptides B and B1
• Synonyms gene
  • SNRPB1
• Synonyms
  • COD
  • SmB/SmB'
  • Sm-B/B'
  • snRNP-B
• Locus
  20p13
• Discovery year
  1988-11-28
• Entrez gene record
  6628
• Pubmed identfication
  • 1376292
• Classification
  • Small nucleolar RNA protein coding host genes
  • Sm spliceosomal proteins
• VEGA ID
  OTTHUMG00000031694

Gene info

• Identity
  HGNC:8499
• Gene
  ORM2
• Long gene name
  orosomucoid 2
• Synonyms
  • AGP-B
  • AGP-B'
  • AGP2
• Synonyms name
  • alpha-1-acid glycoprotein, type 2
• Locus
  9q32
• Discovery year
  1991-03-11
• Entrez gene record
  5005
• Pubmed identfication
  • 4711474
  • 2970990
• RefSeq identity
  • NM_000608
• Classification
  • Lipocalins
• VEGA ID
  OTTHUMG00000021014

Gene info

• Identity
  HGNC:3424
• Gene
  ERAL1
• Long gene name
  Era like 12S mitochondrial rRNA chaperone 1
• Synonyms gene name
  • Era (E. coli G-protein homolog)-like 1
  • Era G-protein-like 1 (E. coli)
  • Era-like 12S mitochondrial rRNA chaperone 1
• Synonyms
  • HERA-B
• GenBank acession
  • AF082657
• Locus
  17q11.2
• Discovery year
  1999-11-19
• Entrez gene record
  26284
• Pubmed identfication
  • 10945472
  • 20604745
• VEGA ID
  OTTHUMG00000132675

Gene info

• Identity
  HGNC:8181
• Gene
  OR1B1
• Long gene name
  olfactory receptor family 1 subfamily B member 1
• Synonyms gene name
  • olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene)
  • olfactory receptor family 1 subfamily B member 1 (gene/pseudogene)
• Synonyms
  • OR9-B
• GenBank acession
  • AC006313
• Locus
  9q33.2
• Discovery year
  1999-12-09
• Entrez gene record
  347169
• RefSeq identity
  • NM_001004450
• Classification
  • Olfactory receptors, family 1
• VEGA ID
  OTTHUMG00000020616

Gene info

• Identity
  HGNC:11242
• Gene
  SPIB
• Long gene name
  Spi-B transcription factor
• Synonyms gene name
  • Spi-B transcription factor (Spi-1/PU.1 related)
• Synonyms
  • SPI-B
• Locus
  19q13.33
• Discovery year
  1994-12-15
• Entrez gene record
  6689
• Pubmed identfication
  • 1406622
• RefSeq identity
  • NM_003121
• Classification
  • ETS transcription factor family
• VEGA ID
  OTTHUMG00000183039

Gene info

• Identity
  HGNC:30578
• Gene
  EXPH5
• Long gene name
  exophilin 5
• Synonyms
  • SLAC2-B
• Synonyms name
  • synaptotagmin-like homologue lacking C2 domains b
• Locus
  11q22.3
• Discovery year
  2005-10-04
• Entrez gene record
  23086
• Pubmed identfication
  • 9734811
  • 11773082
• RefSeq identity
  • NM_015065
• VEGA ID
  OTTHUMG00000166536

Gene info

• Identity
  HGNC:4932
• Gene
  HLA-B
• Long gene name
  major histocompatibility complex, class I, B
• Synonyms gene
  • AS
• Synonyms gene name
  • ankylosing spondylitis
• GenBank acession
  • M15470
• Locus
  6p21.33
• Discovery year
  2001-06-22
• Entrez gene record
  3106
• Pubmed identfication
  • 3459708
• RefSeq identity
  • NM_005514
• Classification
  • C1-set domain containing
  • Histocompatibility complex
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000031153
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:9956
• Gene
  RELB
• Long gene name
  RELB proto-oncogene, NF-kB subunit
• Synonyms gene name
  • v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
• Synonyms
  • REL-B
• GenBank acession
  • M83221
• Locus
  19q13.32
• Discovery year
  1995-10-02
• Entrez gene record
  5971
• Pubmed identfication
  • 1531086
• Classification
  • IPT domain containing
  • NF-kappa B complex subunits
• VEGA ID
  OTTHUMG00000162116

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products