Recombinant Human Palmitoyl-Protein Thioesterase 1/PPT1 Protein(C-6His) 50µg

• Catalog number
  PKSH032848-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  Palmitoyl-protein thioesterase 1;PPT-1;Palmitoyl-protein hydrolase 1;PPT1
• Activity
  NA
• Sequence
  Asp28-Gly306
• Fusion tag
  C-6His
• Accession
  P50897
• Expressed Host
  Human cells
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞90% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
• Mol Mass
  32.3 kDa
• AP Mol Mass
  37 kDa
• Formulation
  Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,10%Glycerol,pH7.5.
• Reconstitution
  Please refer to it for detailed information.
• Background
  Palmitoyl-protein thioesterase 1(PPT-1 for short), also known as Palmitoyl-protein hydrolase 1, belongs to the palmitoyl-protein thioesterase family. It is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. This enzyme removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Defects in PPT1 are the cause of neuronal ceroid lipofuscinosis type 1.
• Product URL
• PDF URL
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Palmitoyl-Protein   Thioesterase   1/PPT1   Protein   C-6His   50µg  
• Gene symbol
  PPT1
• Short name
  Recombinant Palmitoyl-Protein Thioesterase 1/PPT1 Protein(C-6His) 50µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Palmitoyl-Protein Thioesterase 1/palmitoyl-protein thioesterase 1 Protein(C-6His) 50µg
• Alternative technique
  rec
• Alternative to gene target
  palmitoyl-protein thioesterase 1, CLN1 and INCL and PPT, PPT1 and IDBG-96867 and ENSG00000131238 and 5538, palmitoyl-CoA hydrolase activity, nuclei, Ppt1 and IDBG-184539 and ENSMUSG00000028657 and 19063, BT.101768 and IDBG-640822 and ENSBTAG00000013367 and 281421

Gene info

• Identity
  HGNC:9325
• Gene
  PPT1
• Long gene name
  palmitoyl-protein thioesterase 1
• Synonyms gene
  • PPT
• Synonyms
  • CLN1
  • INCL
• Synonyms name
  • ceroid-lipofuscinosis, neuronal 1, infantile
• GenBank acession
  • U44772
• Locus
  1p34.2
• Discovery year
  2000-06-09
• Entrez gene record
  5538
• Pubmed identfication
  • 7637805
  • 8325646
• RefSeq identity
  • NM_000310
• Classification
  • Depalmitoylases
• VEGA ID
  OTTHUMG00000004495
• Locus Specific Databases
  • Neuronal Ceroid Lipofuscinoses; NCL Mutations
  • Mutations of the Palmitoyl-Protein Thioesterase Gene (PPT CLN1) Gene
  • LRG_690

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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