Recombinant Human Nucleoside Diphosphate Kinase A/NDPKA Protein(N-6His)

• Catalog number
  PKSH032830-10µg
• Price
  Please ask
• Size
  10µg

• Synonym
  Nucleoside Diphosphate Kinase A; NDK A; NDP Kinase A; Granzyme A-Activated DNase; GAAD; Metastasis Inhibition Factor nm23; Tumor Metastatic Process-Associated Protein; nm23-H1; NME1; NDPKA; NM23
• Activity
  NA
• Sequence
  Met1-Glu152
• Fusion tag
  N-6His
• Accession
  P15531
• Expressed Host
  E.coli
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞90% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
• Mol Mass
  19.3 kDa
• AP Mol Mass
  20 kDa
• Formulation
  Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 1mM DTT, 10% Glycerol, pH 7.5.
• Background
  Nucleoside-Diphosphate Kinases (NDKs) are enzymes that catalyze the exchange of phosphate groups between different nucleoside diphosphates. NDKs Possesse nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3-5 exonuclease activities. NDKs involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression and required for neural development including neural patterning and cell fate determination. Prokaryotic NDK forms a functional homotetramer.There are two isoforms of NDK in humans: NDK-A and NDK-B. Both have very similar structure, and can combine in any proportion to form functional NDK hexamers.
• Technical data
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Nucleoside   Diphosphate   Kinase   A/NDPKA   Protein   N-6His  
• Gene symbol
  NME1
• Short name
  Recombinant Nucleoside Diphosphate Kinase A/NDPKA Protein(N-6His)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Nucleoside Diphosphate phosphorylation catalyst A/NDPKA Protein(N-6His)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:7849
• Gene
  NME1
• Long gene name
  NME/NM23 nucleoside diphosphate kinase 1
• Synonyms gene name
  • non-metastatic cells 1, protein (NM23A) expressed in
• Synonyms
  • NM23
  • NM23-H1
  • NDPKA
• GenBank acession
  • AL360191
  • X17620
• Locus
  17q21.33
• Discovery year
  1991-07-26
• Entrez gene record
  4830
• Pubmed identfication
  • 8270257
  • 19852809
• RefSeq identity
  • NM_000269
• Classification
  • NME/NM23 family
  • SET complex
• VEGA ID
  OTTHUMG00000137474

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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