Recombinant Human NTPDase 2 / ENTPD2 Protein (aa 29-460, His tag) 20µg

• Catalog number
  PKSH031019-20µg
• Price
  Please ask
• Size
  20µg

• Synonym
  CD39L1;NTPDase-2;RP11-229P13.11-001
• Activity
  Measured by its ability to hydrolyze the 5’phosphate groups from the substrate adenosine 5’triphosphate(ATP).The specific activity is > 5,000 pmoles/min/μg.
• Sequence
  Thr29-Asp460
• Fusion tag
  N-His
• Accession
  Q9Y5L3
• Expressed Host
  Baculovirus-Insect Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞85 % as determined by SDS-PAGE
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  49.3 kDa
• AP Mol Mass
  59 kDa
• Formulation
  Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4
• Reconstitution
  Please refer to it for detailed information.
• Background
  NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; the main role of these enzymes is the termination of purinergic signaling. NTPDases are ubiquitous and were previously shown in other parasites including the trypanosomatides of genus Leishmania and in T. brucei. NTPase activity would act as a timer and is crucial to T. gondii infection. In L. pneumophila it was demonstrated that an E-NTPDase, similar to CD39, is essential for intracellular bacterial multiplication. NTPDase 2 is an integral membrane protein. In the nervous system, it could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Alternative splicing of NTPDase 2 gene results in multiple transcript variants.
• Product URL
• PDF URL
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  NTPDase   ENTPD2   Protein   29-460   His   tag   20µg  
• Gene symbol
  SNORD114-29, SNORD115-29, SNORD116-29, IGHV3-29, IGLV3-29, IGKV2-29, ERVK-29, IGKV2D-29, ERVW-29, RNVU1-29
• Short name
  Recombinant NTPDase 2 / ENTPD2 Protein (aa 29-460, His tag) 20µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens NTPDase 2 / ectonucleoside triphosphate diphosphohydrolase 2 Protein (aa 29-460, histidine detection labelled) 20µg
• Alternative technique
  rec
• Alternative to gene target
  ectonucleoside triphosphate diphosphohydrolase 2, CD39L1 and NTPDase-2, ENTPD2 and IDBG-93039 and ENSG00000054179 and 954, nucleoside-triphosphatase activity, Plasma membranes, Entpd2 and IDBG-145500 and ENSMUSG00000015085 and 12496, ENTPD2 and IDBG-641330 and ENSBTAG00000048125 and 100126045

Gene info

• Identity
  HGNC:33017
• Gene
  SNORD114-29
• Long gene name
  small nucleolar RNA, C/D box 114-29
• Synonyms
  • 14q(II-29)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767610
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003222.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33048
• Gene
  SNORD115-29
• Long gene name
  small nucleolar RNA, C/D box 115-29
• Synonyms
  • HBII-52-29
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033803
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003344.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33348
• Gene
  SNORD116-29
• Long gene name
  small nucleolar RNA, C/D box 116-29
• Synonyms
  • HBII-85-29
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-16
• Entrez gene record
  100033821
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003360
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5590
• Gene
  IGHV3-29
• Long gene name
  immunoglobulin heavy variable 3-29 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable 3-29
  • immunoglobulin heavy variable 3-29 pseudogene
• GenBank acession
  • M99662
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28440
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000188328

Gene info

• Identity
  HGNC:5911
• Gene
  IGLV3-29
• Long gene name
  immunoglobulin lambda variable 3-29 (pseudogene)
• Synonyms gene name
  • immunoglobulin lambda variable 3-29
• GenBank acession
  • Z73644
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28790
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151168

Gene info

• Identity
  HGNC:5784
• Gene
  IGKV2-29
• Long gene name
  immunoglobulin kappa variable 2-29
• Synonyms gene name
  • immunoglobulin kappa variable 2-29 (gene/pseudogene)
• GenBank acession
  • X63396
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28920
• RefSeq identity
  • NG_000834
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151641

Gene info

• Identity
  HGNC:44982
• Gene
  ERVK-29
• Long gene name
  endogenous retrovirus group K member 29
• Synonyms gene name
  • endogenous retrovirus group K, member 29
• GenBank acession
  • JZ164912
• Locus
  19q13.12
• Discovery year
  2014-01-03
• Pubmed identfication
  • 23338945

Gene info

• Identity
  HGNC:5800
• Gene
  IGKV2D-29
• Long gene name
  immunoglobulin kappa variable 2D-29
• GenBank acession
  • M31952
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28882
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151619

Gene info

• Identity
  HGNC:49378
• Gene
  ERVW-29
• Long gene name
  endogenous retrovirus group W member 29
• Synonyms gene name
  • endogenous retrovirus group W, member 29
• GenBank acession
  • HG421066
• Locus
  18p11.21
• Discovery year
  2013-10-21

Gene info

• Identity
  HGNC:54433
• Gene
  RNVU1-29
• Long gene name
  RNA, variant U1 small nuclear 29
• Locus
  1q21.1
• Discovery year
  2019-07-26
• Classification
  • Variant U1 small nuclear RNAs

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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