Recombinant Human Natural Cytotoxicity Triggering Receptor 1/NCR1/NKp46/CD335 Protein(C-Fc)
-
Catalog number
PKSH032783-10µg
-
Price
Please ask
-
Size
10µg
-
-
Synonym
Natural cytotoxicity triggering receptor 1;Lymphocyte antigen 94 homolog;NK cell-activating receptor;Natural killer cell p46-related protein;NK-p46;NKp46;hNKp46;CD335;NCR1;LY94;
-
Activity
NA
-
Sequence
Gln22-Asn254
-
Fusion tag
C-Fc
-
Accession
O76036
-
Expressed Host
Human cells
-
Shipping
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
-
Purity
＞95% as determined by reducing SDS-PAGE.
-
Endotoxin
＜1.0 EU per µg as determined by LAL test.
-
Stability and Storage
Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
-
Mol Mass
53.5 kDa
-
AP Mol Mass
60 kDa
-
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
-
Background
Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is a natural killer (NK) lymphocyte-activating receptor. It is involved in major aspects of NK immune function and shows a high degree of lineage specificity in blood and bone marrow.
-
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
-
Source
Recombinants or rec. proteins
-
Group
recombinants
-
Gene target
-
Gene symbol
NCR1
-
Short name
Recombinant Natural Cytotoxicity Triggering Receptor 1/NCR1/NKp46/CD335 Protein(C-Fc)
-
Technique
Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
-
Species
Human, Humans
-
Alternative name
Rec. H. sapiens Natural Cytotoxicity Triggering Receptor 1/natural cytotoxicity triggering receptor 1/NKp46/CD335 Protein(C-fragment c)
-
Alternative technique
rec
-
Alternative to gene target
natural cytotoxicity triggering receptor 1, CD335 and LY94 and NK-p46 and NKP46, NCR1 and IDBG-69753 and ENSG00000189430 and 9437, receptor signaling protein activity, Plasma membranes, Ncr1 and IDBG-137680 and ENSMUSG00000062524 and 17086, NCR1 and IDBG-641998 and ENSBTAG00000045529 and 369024
-
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
