Recombinant Human N-myc Downstream Regulated Gene 1/NDRG1/DRG-1CAP43 Protein(N-6His) 50µg

• Catalog number
  PKSH032818-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  Protein NDRG1; Differentiation-Related Gene 1 Protein; DRG-1; N-myc Downstream-Regulated Gene 1 Protein; Nickel-Specific Induction Protein Cap43; Reducing Agents and Tunicamycin-Responsive Protein; RTP; Rit42; NDRG1; CAP43; DRG1; RTP
• Activity
  NA
• Sequence
  Met1-Cys394
• Fusion tag
  N-6His
• Accession
  Q92597
• Expressed Host
  E.coli
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞90% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
• Mol Mass
  45.0 kDa
• AP Mol Mass
  52 kDa
• Formulation
  Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
• Reconstitution
  Please refer to it for detailed information.
• Background
  Protein NDRG1 is a member of the N-Myc Downregulated Gene family, which is part of the α/β Hydrolase superfamily. Protein NDRG1 is a cytoplasmic protein that is involved in stress responses, hormone responses, cell growth and differentiation. Protein NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Protein NDRG1 mutuations are reported to be the cause for hereditary motor and sensory neuropathy-Lom. Decreased NDRG1 expression in glioma is linked to tumor progression; overexpression of NDRG1 is connected to malignant status of esophageal cancer.
• Product URL
• PDF URL
• Description
  cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  N-myc   Downstream   Regulated   Gene   1/NDRG1/DRG-1CAP43   Protein   N-6His   50µg  
• Gene symbol
  NDRG1
• Short name
  Recombinant N-myc Downstream Regulated 1/NDRG1/DRG-1CAP43 Protein(N-6His) 50µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens N-v-myc myelocytomatosis viral oncogene homolog (avian) Downstream Regulated Gene 1/N-v-myc myelocytomatosis viral oncogene homolog (avian) downstream regulated 1/DRG-1CAP43 Protein(N-6His) 50µg
• Alternative technique
  rec
• Alternative to gene target
  v-myc myelocytomatosis viral oncogene homolog (avian), bHLHe39 and c-Myc and MRTL and MYCC, MYC and IDBG-35442 and ENSG00000136997 and 4609, E-box binding, nuclei, Bmyc and IDBG-147082 and ENSMUSG00000049086 and 107771, MYC and IDBG-644147 and ENSBTAG00000008409 and 511077

Gene info

• Identity
  HGNC:7679
• Gene
  NDRG1
• Long gene name
  N-myc downstream regulated 1
• Synonyms gene
  • CAP43
• Synonyms
  • DRG1
  • RTP
  • TDD5
  • NDR1
• GenBank acession
  • X92845
• Locus
  8q24.22
• Discovery year
  1998-12-23
• Entrez gene record
  10397
• Pubmed identfication
  • 9251681
  • 8939898
  • 18455888
• Classification
  • NDRG family
• VEGA ID
  OTTHUMG00000164441
• Locus Specific Databases
  • Inherited Peripheral Neuropathies Mutation Database
  • LRG_258

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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