Recombinant Human Mitochondrial Fission 1 Protein/FIS1 Protein(C-6His)
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Catalog number
PKSH032758-10µg
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Price
Please ask
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Size
10µg
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Synonym
Mitochondrial Fission 1 Protein; FIS1 Homolog; hFis1; Tetratricopeptide Repeat Protein 11; TPR Repeat Protein 11; FIS1; TTC11; CGI-135
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Activity
NA
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Sequence
Met1-Gly122
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Fusion tag
C-6His
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Accession
Q9Y3D6
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Expressed Host
E.coli
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Shipping
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
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Purity
＞95% as determined by reducing SDS-PAGE.
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Endotoxin
＜1.0 EU per µg as determined by LAL test.
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Stability and Storage
Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
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Mol Mass
15.2 kDa
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AP Mol Mass
14 kDa
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Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM Tris, pH 8.0.
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Background
Mitochondrial Fission 1 Protein (FIS1) is a member of the FIS1 family. FIS1 is a single-pass membrane protein and contains one TPR repeat. FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 can induce cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. In addition, FIS1 participates in peroxisomal growth and division. The C-terminus of FIS1 is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
FIS1
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Short name
Recombinant Mitochondrial Fission 1 Protein/FIS1 Protein(C-6His)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Human, Humans
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Alternative name
Rec. H. sapiens Mitochondrial Fission 1 Protein/fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) Protein(C-6His)
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Alternative technique
rec
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Alternative to gene target
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae), FIS1 and IDBG-234267 and ENSG00000214253 and 51024, protein binding, Plasma membranes, Fis1 and IDBG-204681 and ENSMUSG00000019054 and 66437, FIS1 and IDBG-640356 and ENSBTAG00000007900 and 615565
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Tissue
mitochondrial
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Gene info
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Identity
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Gene
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Long gene name
fission, mitochondrial 1
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Synonyms gene
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Synonyms gene name
- tetratricopeptide repeat domain 11
- fission 1 (mitochondrial outer membrane) homolog (yeast)
- fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2003-07-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tetratricopeptide repeat domain containing
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Radioimmunoassay of proteins using antibody coupled to an immunosorbent.
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Tree numbers
- E05.478.566.380.830
- E05.478.566.639.830
- E05.601.470.380.830
- E05.601.470.639.830
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Qualifiers
ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data
Product images
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