Recombinant Human Mannoside Acetylglucosaminyltransferase 2/GlcNAc-TII Protein(C-6His)

  • Catalog number
    PKSH032737-10µg
  • Price
    Please ask
  • Size
    10µg
  • Synonym
    Alpha-1;6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase; Beta-1;2-N-acetylglucosaminyltransferase II; GlcNAc-T II; NT-II; Mannoside Acetylglucosaminyltransferase 2; N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II; MGAT2
  • Activity
    NA
  • Sequence
    Arg30-Gln447
  • Fusion tag
    C-6His
  • Accession
    Q10469
  • Expressed Host
    Human cells
  • Shipping
    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
  • Purity
    >95% as determined by reducing SDS-PAGE.
  • Endotoxin
    <1.0 EU per µg as determined by LAL test.
  • Stability and Storage
    Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
  • Mol Mass
    49.3 kDa
  • AP Mol Mass
    50 kDa
  • Formulation
    Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl, pH8.0 .
  • Background
    Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Short name
    Recombinant Mannoside Acetylglucosaminyltransferase 2/GlcNAc-TII Protein(C-6His)
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    Rec. H. sapiens Mannoside Acetylglucosaminyltransferase 2/GlcNAc-TII Protein(C-6His)
  • Alternative technique
    rec
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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