Recombinant Human Lysosomal Pro-X Carboxypeptidase/PRCP Protein(C-6His) 50µg
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Catalog numberPKSH032721-50µg
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PricePlease ask
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Size50µg
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SynonymLysosomal Pro-X Carboxypeptidase; Angiotensinase C; Lysosomal Carboxypeptidase C; Proline Carboxypeptidase; Prolylcarboxypeptidase; PRCP; PRCP; PCP
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ActivityNA
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SequenceLeu22-His496
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Fusion tagC-6His
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AccessionP42785
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Expressed HostHuman cells
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ShippingThe product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
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Purity>95% as determined by reducing SDS-PAGE.
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Endotoxin<1.0 EU per µg as determined by LAL test.
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Stability and StorageStore at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
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Mol Mass54.5 kDa
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AP Mol Mass72 kDa
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FormulationSupplied as a 0.2 μm filtered solution of 20mM NaAc-HAc,150mM NaCl,10%Glycerol,pH4.5.
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ReconstitutionPlease refer to it for detailed information.
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BackgroundLysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolPRCP
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Short nameRecombinant Lysosomal Pro-X Carboxypeptidase/PRCP Protein(C-6His) 50µg
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameRec. H. sapiens Lysosomal L-proline-X Carboxypeptidase/PRCP Protein(C-6His) 50µg
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene nameprolylcarboxypeptidase
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Synonyms gene name
- prolylcarboxypeptidase (angiotensinase C)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-11-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Minor histocompatibility antigens
- M14 carboxypeptidases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data