Recombinant Human Kallikrein 1/KLK1 Protein(C-6His) 50µg

• Catalog number
  PKSH032664-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  Kallikrein-1; Kidney/Pancreas/Salivary Gland Kallikrein; Tissue Kallikrein; KLK1
• Activity
  NA
• Sequence
  Pro19-Ser262
• Fusion tag
  C-6His
• Accession
  P06870
• Expressed Host
  Human cells
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
• Mol Mass
  28.2 kDa
• AP Mol Mass
  38 kDa
• Formulation
  Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, 2mM CaCl2, pH 8.0.
• Reconstitution
  Please refer to it for detailed information.
• Background
  Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays a role in angiogensis and tumorigenesis.
• Product URL
• PDF URL
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Kallikrein   1/KLK1   Protein   C-6His   50µg  
• Gene symbol
  KLK1
• Short name
  Recombinant Kallikrein 1/KLK1 Protein(C-6His) 50µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Kallikrein 1/KLK1 Protein(C-6His) 50µg
• Alternative technique
  rec

Gene info

• Identity
  HGNC:6357
• Gene
  KLK1
• Long gene name
  kallikrein 1
• Synonyms gene name
  • kallikrein 1, renal/pancreas/salivary
• Synonyms
  • Klk6
• GenBank acession
  • L10038
• Locus
  19q13.33
• Discovery year
  1988-06-27
• Entrez gene record
  3816
• Pubmed identfication
  • 1684954
  • 16800724
  • 16800723
• RefSeq identity
  • NM_002257
• Classification
  • Kallikreins
• VEGA ID
  OTTHUMG00000182876

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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