Recombinant Human ITGAX & ITGB2 Heterodimer Protein

Synonym

CD11C;SLEB6
Activity

NA
Sequence

Met 1-Pro 1107
Fusion tag

NA
Accession

P20702
Expressed Host

HEK293 Cells
Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Purity

> 90 % as determined by SDS-PAGE
Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method
Stability and Storage

Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Mol Mass

205 (125+80) kDa
AP Mol Mass

95 &130 kDa
Formulation

Lyophilized from sterile PBS, pH 7.4
Background

NA
Technical data
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

ITGAX ITGB2 Heterodimer Protein
Gene symbol

ITGB2-AS1, ITGAX, ITGB2
Short name

Recombinant ITGAX & ITGB2 Heterodimer Protein
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

Rec. H. sapiens integrin, alpha X (complement component 3 receptor 4 subunit) & integrin, b 2 (complement component 3 receptor 3 and 4 subunit) Heterodimer Protein
Alternative technique

rec
Alternative to gene target

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), CD18 and LAD and LCAMB and LFA-1 and MAC-1 and MF17 and MFI7, ITGB2 and IDBG-5590 and ENSG00000160255 and 3689, metal ion binding, Cell surfaces, ITGB2 and IDBG-639611 and ENSBTAG00000017060 and 281877

Identity

HGNC:6152
Gene

ITGAX
Long gene name

integrin subunit alpha X
Synonyms gene
- CD11C
Synonyms gene name
- integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
- integrin, alpha X (complement component 3 receptor 4 subunit)
Synonyms
- CD11c
Synonyms name
- complement component 3 receptor 4 subunit
GenBank acession
- BC038237
Locus

16p11.2
Discovery year

1988-08-15
Entrez gene record

3687
Pubmed identfication
- 3284962
- 2303426
RefSeq identity
- NM_000887
Classification
- Integrin alpha subunits
- Complement system regulators and receptors
- CD molecules
VEGA ID

OTTHUMG00000132465

Identity

HGNC:6155
Gene

ITGB2
Long gene name

integrin subunit beta 2
Synonyms gene
- CD18
- MFI7
Synonyms gene name
- integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
- integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
Synonyms
- LFA-1
- MAC-1
Synonyms name
- complement component 3 receptor 3 and 4 subunit
GenBank acession
- AK222505
Locus

21q22.3
Discovery year

1986-01-01
Entrez gene record

3689
RefSeq identity
- NM_000211
Classification
- Integrin beta subunits
- Complement system regulators and receptors
- CD molecules
VEGA ID

OTTHUMG00000090257
Locus Specific Databases
- ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I)
- LRG_76

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data