Recombinant Human IL13 Protein (Fc Tag) 20µg
-
Catalog number
PKSH032457 -20µg
-
Price
Please ask
-
Size
20µg
-
-
Synonym
ALRH;IL-13;P600
-
Activity
Measured by its binding ability in a functional ELISA. Immobilized recombinant human IL13RA2 at 8 μg/ml (100 μl/well) can bind IL13 with a linear range of 0.25-8.0 ng/ml.
-
Sequence
Gly 21-Asn 132
-
Fusion tag
Fc Tag
-
Accession
AAK53823.1
-
Expressed Host
HEK293 Cells
-
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
-
Purity
＞98 % as determined by SDS-PAGE
-
Endotoxin
＜1.0 EU per µg as determined by the LAL method
-
Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Mol Mass
39 kDa
-
AP Mol Mass
50-55 kDa
-
Formulation
Lyophilized from sterile PBS, pH 7.4
-
Reconstitution
Please refer to it for detailed information.
-
Background
Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
-
Product URL
#N/A
-
PDF URL
#N/A
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Source
Recombinants or rec. proteins
-
Group
recombinants
-
Gene target
-
Gene symbol
IL13
-
Short name
Recombinant IL13 Protein (Fc Tag) 20µg
-
Technique
Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
-
Label
Fc Tag
-
Species
Human, Humans
-
Alternative name
Rec. H. sapiens interleukin 13 Protein (fragment c detection labelled) 20µg
-
Alternative technique
rec
-
Alternative to gene target
interleukin 13, IL-13 and P600, IL13 and IDBG-42599 and ENSG00000169194 and 3596, protein binding, Extracellular, Il13 and IDBG-172064 and ENSMUSG00000020383 and 16163, IL13 and IDBG-644674 and ENSBTAG00000015953 and 281247
-
Gene info
-
Identity
-
Gene
-
Long gene name
interleukin 13
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1993-04-07
-
Entrez gene record
-
RefSeq identity
-
Classification
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
-
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
