Recombinant Human FABP2 / I-FABP Protein (His tag) 200µg

  • Catalog number
    PKSH031845-200µg
  • Price
    Please ask
  • Size
    200µg
  • Synonym
    FABPI;I-FABP;MGC133132
  • Activity
    NA
  • Sequence
    Met 1-Asp 132
  • Fusion tag
    C-His
  • Accession
    P12104-1
  • Expressed Host
    E. coli
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    >95 % as determined by SDS-PAGE
  • Endotoxin
    Please contact us for more information.
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    16.6 kDa
  • AP Mol Mass
    17 kDa
  • Formulation
    Lyophilized from sterile PBS, pH 7.5
  • Reconstitution
    Please refer to it for detailed information.
  • Background
    Fatty acid binding protein (FABP) is one of the intracellular proteins, with a low molecular weight of approximately 15 kDa, that plays important roles in the transportation and metabolism of long-chain fatty acids. FABP family proteins could be used as tissue specific injury marker based on the following characteristics of FABP. The intestinal fatty acid binding protein (I-FABP), or fatty acid-binding protein 2 (FABP2), an intracellular protein expressed only in the intestine, involved in the absorption and intracellular transport of dietary long chain fatty acids. The FABP2 gene is proposed as a candidate gene for diabetes because the protein it codes is involved in fatty acid (FA) absorption and metabolism. Numerous studies have assessed FABP2 gene variants. A transition of G to A at codon 54 of FABP2 results in an amino acid substitution (Ala54 to Thr54), which is common in diverse populations and results in increased FA absorption in vivo. Some evidence indicates that this variant may be associated with type 2 diabetes. This polymorphism was associated with some cardiovascular risk factors. The cytosolic human intestinal fatty acid binding protein (hFABP2) is proposed to be involved in intestinal absorption of long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
  • Conjugation
    histidine
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    FABP2   I-FABP   Protein   His   tag   200µg  
  • Gene symbol
    FABP2, FABP5, FABP3, FABP1, FABP6, FABP7, FABP4, FABP9, PMP2, TANK
  • Short name
    Recombinant FABP2 / I-FABP Protein (His tag) 200µg
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Label
    His
  • Species
    Human, Humans
  • Alternative name
    Rec. H. sapiens FABP2 / I-FABP Protein (histidine detection labelled) 200µg
  • Alternative technique
    rec
Gene info
  • Identity
  • Gene
  • Long gene name
    fatty acid binding protein 2
  • Synonyms gene name
    • fatty acid binding protein 2, intestinal
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1986-01-01
  • Entrez gene record
  • RefSeq identity
  • Classification
    • Fatty acid binding protein family
  • VEGA ID
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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