Recombinant Human Diamine Oxidase/DAO/AOC1 Protein(C-6His)

• Catalog number
  PKSH032352-10µg
• Price
  Please ask
• Size
  10µg

• Synonym
  Amiloride-sensitive amine oxidase [copper-containing];DAO;Diamine oxidase;Amiloride-binding protein 1;Amine oxidase copper domain-containing protein 1;Histaminase;Kidney amine oxidase;KAO;AOC1;ABP1; DAO1
• Activity
  NA
• Sequence
  Glu20-Val751
• Fusion tag
  C-6His
• Accession
  P19801
• Expressed Host
  Human cells
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
• Mol Mass
  84.4 kDa
• AP Mol Mass
  90 kDa
• Formulation
  Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl,10% Glycerol,pH7.5.
• Background
  Amiloride-sensitive amine oxidase (AOC1) belongs to the copper/topaquinone oxidase family. The protein exists as homodimer by disulfide and mainly located in placenta and kidney. AOC1 catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. The activity of this protein can be inhibited by amiloride in a competitive manner. It is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.
• Technical data
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Diamine   Oxidase/DAO/AOC1   Protein   C-6His  
• Gene symbol
  AOC1, DAO
• Short name
  Recombinant Diamine Oxidase/DAO/AOC1 Protein(C-6His)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Diamine Oxidase/DAO/AOC1 Protein(C-6His)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:80
• Gene
  AOC1
• Long gene name
  amine oxidase copper containing 1
• Synonyms gene
  • ABP1
  • ABP
• Synonyms gene name
  • amiloride binding protein 1 (amine oxidase (copper-containing))
• Synonyms
  • DAO
• Synonyms name
  • diamine oxidase
• GenBank acession
  • AK092514
• Locus
  7q36.1
• Discovery year
  1991-05-06
• Entrez gene record
  26
• Pubmed identfication
  • 8182053
• RefSeq identity
  • NM_001091
• VEGA ID
  OTTHUMG00000158306

Gene info

• Identity
  HGNC:2671
• Gene
  DAO
• Long gene name
  D-amino acid oxidase
• Synonyms
  • DAMOX
  • DAAO
• GenBank acession
  • D11370
• Locus
  12q24.11
• Discovery year
  1992-11-25
• Entrez gene record
  1610
• Pubmed identfication
  • 1356107
• VEGA ID
  OTTHUMG00000169360

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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