Recombinant Human CLEC10A / MGL1 / CD301 Protein (Fc tag)
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Catalog number
PKSH031411-50µg
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Price
Please ask
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Size
50µg
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Synonym
CD301;CLECSF13;CLECSF14;HML;HML2;MGL
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Activity
NA
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Sequence
Gln61-His292
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Fusion tag
N-Fc
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Accession
Q8IUN9-2
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Expressed Host
HEK293 Cells
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
＞85 % as determined by SDS-PAGE
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Endotoxin
＜1.0 EU per µg as determined by the LAL method
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
54.6 kDa
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AP Mol Mass
58 kDa
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Formulation
Lyophilized from sterile PBS, pH 7.4
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Background
CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). There are 2 homologues: MGL1 and MGL2 (CD301a and CD301b) in mice. MGL1/CD301a induces both the production and secretion of interleukin (IL)-10. MGL1/CD301a plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
CLEC10A, LLGL1
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Short name
Recombinant CLEC10A / MGL1 / CD301 Protein (Fc tag)
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Technique
Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Label
Fc Tag
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Species
Human, Humans
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Alternative name
Rec. H. sapiens C-classification lectin domain family 10, member A / MGL1 / CD301 Protein (fragment c detection labelled)
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Alternative technique
rec
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Alternative to gene target
C-type lectin domain family 10, member A, CD301 and CLECSF13 and CLECSF14 and HML and HML2 and MGL, CLEC10A and IDBG-23148 and ENSG00000132514 and 10462, carbohydrate binding, Plasma membranes, CLEC10A and IDBG-634544 and ENSBTAG00000017895 and 514833
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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