Recombinant Human CD31 / PECAM1 Protein 50µg

• Catalog number
  PKSH030474-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  CD31;CD31/EndoCAM;endoCAM;GPIIA';PECA1;PECAM-1
• Activity
  NA
• Sequence
  Met1-Lys 601
• Fusion tag
  NA
• Accession
  EAW94208.1
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞95 % as determined by SDS-PAGE
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  65.1 kDa
• AP Mol Mass
  115 kDa
• Formulation
  Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5
• Reconstitution
  Please refer to it for detailed information.
• Background
  The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
• Product URL
• PDF URL
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CD31   PECAM1   Protein   50µg  
• Gene symbol
  PECAM1
• Short name
  Recombinant CD31 / PECAM1 Protein 50µg
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens CD31 / PECAM1 Protein 50µg
• Alternative technique
  rec

Gene info

• Identity
  HGNC:8823
• Gene
  PECAM1
• Long gene name
  platelet and endothelial cell adhesion molecule 1
• Synonyms gene name
  • platelet/endothelial cell adhesion molecule 1
• Synonyms
  • CD31
• Synonyms name
  • CD31 antigen
• GenBank acession
  • L34631
  • M37780
• Locus
  17q23.3
• Discovery year
  1995-11-29
• Entrez gene record
  5175
• Pubmed identfication
  • 8661055
  • 1690453
• RefSeq identity
  • NM_000442
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
  • Ig-like cell adhesion molecule family
• VEGA ID
  OTTHUMG00000175829

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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