Recombinant Human Carboxypeptidase M/CPM Protein(C-6His)

• Catalog number
  PKSH032174-10µg
• Price
  Please ask
• Size
  10µg

• Synonym
  Carboxypeptidase M;CPM
• Activity
  NA
• Sequence
  Leu18-His422
• Fusion tag
  C-6His
• Accession
  P14384
• Expressed Host
  Human cells
• Shipping
  The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
• Purity
  ＞95% as determined by reducing SDS-PAGE.
• Endotoxin
  ＜1.0 EU per µg as determined by LAL test.
• Stability and Storage
  Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
• Mol Mass
  47.3 kDa
• AP Mol Mass
  55 kDa
• Formulation
  Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,1mM ZnCl2,pH7.5.
• Background
  Carboxypeptidase M (CPM) specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. Carboxypeptidase exert roles in the physiological processes of blood coagulation/fibrinolysis, inflammation, food digestion and pro-hormone and neuropeptide processing. CPM is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins. It is widely distributed in a variety of tissues and cells. CPM is involved in peptide metabolism on both the cell surface and in extracellular fluids. CPM functions not only as a protease but also as a binding partner in cell-surface protein-protein interactions.
• Technical data
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Carboxypeptidase   M/CPM   Protein   C-6His  
• Gene symbol
  CPM
• Short name
  Recombinant Carboxypeptidase M/CPM Protein(C-6His)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Carboxypeptidase M/CPM Protein(C-6His)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:2311
• Gene
  CPM
• Long gene name
  carboxypeptidase M
• Synonyms name
  • renal carboxypeptidase
  • urinary carboxypeptidase B
• GenBank acession
  • AF368463
• Locus
  12q15
• Discovery year
  1995-09-11
• Entrez gene record
  1368
• Pubmed identfication
  • 8586455
• RefSeq identity
  • NM_198320
• Classification
  • M14 carboxypeptidases
• VEGA ID
  OTTHUMG00000169300

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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