Recombinant Human CANT1 Protein (Fc tag)

• Catalog number
  PKSH030724-10µg
• Price
  Please ask
• Size
  10µg

• Synonym
  DBQD;SCAN-1;SCAN1;SHAPY
• Activity
  NA
• Sequence
  Gly80-Ile401
• Fusion tag
  N-Fc
• Accession
  Q8WVQ1-1
• Expressed Host
  HEK293 Cells
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞90 % as determined by SDS-PAGE
• Endotoxin
  ＜1.0 EU per µg as determined by the LAL method
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  64.3 kDa
• AP Mol Mass
  65 kDa
• Formulation
  Lyophilized from sterile PBS, pH 7.4
• Background
  CANT1(calcium activated nucleotidase 1) belongs to the apyrase family. Apyrase is a calcium-activated plasma membrane-bound enzyme (magnesium can also activate it) (EC 3.6.1.5) that catalyses the hydrolysis of ATP to yield AMP and inorganic phosphate. Two isoenzymes are found in commercial preparations from S. tuberosum. One with a higher ratio of substrate selectivity for ATP: ADP and another with no selectivity. It can also act on ADP and other nucleoside triphosphates and diphosphates with the general reaction being NTP -> NDP + Pi -> NMP + 2Pi. The salivary apyrases of blood-feeding arthropods are nucleotide hydrolysing enzymes are implicated in the inhibition of host platelet aggregation through the hydrolysis of extracellular adenosine diphosphate. CANT1 functions as a calcium-dependent nucleotidase with a preference for UDP. Defects in CANT1 are the cause of desbuquois dysplasia.
• Technical data
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CANT1   Protein   tag  
• Gene symbol
  CANT1
• Short name
  Recombinant CANT1 Protein (Fc tag)
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  Fc Tag
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens CANT1 Protein (fragment c detection labelled)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:19721
• Gene
  CANT1
• Long gene name
  calcium activated nucleotidase 1
• Synonyms
  • SHAPY
  • SCAN-1
• Synonyms name
  • Soluble Ca-Activated Nucleotidase, isozyme 1
  • apyrase 1 homolog (C. lectularius)
• GenBank acession
  • AJ312208
• Locus
  17q25.3
• Discovery year
  2004-02-17
• Entrez gene record
  124583
• Pubmed identfication
  • 12167635
  • 19853239
• RefSeq identity
  • NM_138793
• VEGA ID
  OTTHUMG00000177570

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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