Recombinant Human Bactericidal Permeability-Increasing Protein/BPI/CAP57 Protein(C-6His) 50µg
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Catalog number
PKSH032108-50µg
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Price
Please ask
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Size
50µg
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Synonym
Bactericidal permeability-increasing protein;BPI;CAP57
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Activity
NA
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Sequence
Val32-Lys487
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Fusion tag
C-6His
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Accession
P17213
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Expressed Host
Human cells
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Shipping
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
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Purity
＞95% as determined by reducing SDS-PAGE.
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Endotoxin
＜1.0 EU per µg as determined by LAL test.
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Stability and Storage
Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
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Mol Mass
52.5 kDa
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AP Mol Mass
50 kDa
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Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
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Reconstitution
Please refer to it for detailed information.
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Background
Bactericidal permeability-increasing protein(BPI for short), is a secreted protein which belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family. It exists as a monomer or a disulfide-linked homodimer. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria. This specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. BPI has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, and this activity is inhibited by LPS from P.aeruginosa.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
BPI
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Short name
Recombinant Bactericidal Permeability-Increasing Protein/BPI/CAP57 Protein(C-6His) 50µg
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Human, Humans
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Alternative name
Rec. H. sapiens Bactericidal Permeability-Increasing Protein/bactericidal/permeability-increasing protein/CAP57 Protein(C-6His) 50µg
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Alternative technique
rec
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Alternative to gene target
bactericidal/permeability-increasing protein, BPIFD1 and rBPI, BPI and IDBG-74654 and ENSG00000101425 and 149684,671, lipid binding, Plasma membranes, Bpi and IDBG-211473 and ENSMUSG00000052922 and 329547, BPI and IDBG-642592 and ENSBTAG00000014046 and 280734
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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