Recombinant Human Autophagy Related 4 Homolog C/ATG4C Protein(C-6His) 50µg

  • Catalog number
    PKSH032100-50µg
  • Price
    Please ask
  • Size
    50µg
  • Synonym
    Cysteine Protease ATG4C; AUT-Like 3 Cysteine Endopeptidase; Autophagin-3; Autophagy-Related Cysteine Endopeptidase 3; Autophagy-Related Protein 4 homolog C; ATG4C; APG4C; AUTL1; AUTL3
  • Activity
    NA
  • Sequence
    Met1-Leu458
  • Fusion tag
    C-6His
  • Accession
    Q96DT6
  • Expressed Host
    E.coli
  • Shipping
    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
  • Purity
    >90% as determined by reducing SDS-PAGE.
  • Endotoxin
    <1.0 EU per µg as determined by LAL test.
  • Stability and Storage
    Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
  • Mol Mass
    53.6 kDa
  • AP Mol Mass
    58 kDa
  • Formulation
    Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 10% Glycerol, pH 8.0.
  • Reconstitution
    Please refer to it for detailed information.
  • Background
    Cysteine Protease ATG4C (ATG4C) belongs to the peptidase C54 family. It is required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form which is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ATG4C is a cytoplasmic protein and high expressed in skeletal muscle, liver, testis and heart. ATG4C can be inhibited by N-ethylmaleimide.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
  • Gene symbol
    ATG4C
  • Short name
    Recombinant Autophagy 4 Homolog C/ATG4C Protein(C-6His) 50µg
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    Rec. H. sapiens Autophagy Related 4 Homolog C/ATG4C Protein(C-6His) 50µg
  • Alternative technique
    rec
Gene info
  • Identity
  • Gene
  • Long gene name
    autophagy related 4C cysteine peptidase
  • Synonyms gene
  • Synonyms gene name
    • AUT (S. cerevisiae)-like 1, cysteine endopeptidase; AUT-like 1, cysteine endopeptidase (S. cerevisiae)
    • APG4 autophagy 4 homolog C (S. cerevisiae)
    • ATG4 autophagy related 4 homolog C (S. cerevisiae)
    • autophagy related 4C, cysteine peptidase
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2001-07-13
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Autophagy related
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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