Recombinant Human ANXA5 / Annexin Ⅴ / Annexin A5 Protein

• Catalog number
  PKSH031601-50µg
• Price
  Please ask
• Size
  50µg

• Synonym
  ANX5;ENX2;HEL-S-7;PP4;RPRGL3
• Activity
  NA
• Sequence
  Met 1-Asp 320
• Fusion tag
  NA
• Accession
  P08758
• Expressed Host
  E. coli
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  > 90 % as determined by SDS-PAGE
• Endotoxin
  Please contact us for more information.
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  35.9 kDa
• AP Mol Mass
  34 kDa
• Formulation
  Lyophilized from sterile 50mM Tris, 240mM NaCl, pH 8.5
• Background
  Peptidyl-prolyl cis-trans isomerase A, also known as PPIase A, Rotamase A, Cyclophilin A, Cyclosporin A-binding protein, PPIA and CYPA, is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. PPIA / Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA / Cyclophilin A is secreted by vascular smooth muscle cells in response to inflammatory stimuli, and could thus contribute to atherosclerosis. It is not essential for mammalian cell viability. PPIA / Cyclophilin A can interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.
• Technical data
• Description
  This Annexin V calcium dependent phospholipid binding protein will be downstream of BCL2 pathway and at caspase apoptotic level. Elabscience has more cell death kits and antibodies.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  ANXA5   Annexin   Annexin   Protein  
• Gene symbol
  ANXA5
• Short name
  Recombinant ANXA5 / Annexin Ⅴ / Annexin A5 Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens annexin A5 / Annexin Ⅴ / Annexin A5 Protein
• Alternative technique
  rec
• Alternative to gene target
  annexin A5, ANX5 and ENX2 and HEL-S-7 and PP4 and RPRGL3, ANXA5 and IDBG-36172 and ENSG00000164111 and 308, calcium-dependent phospholipid binding, Cell surfaces, Anxa5 and IDBG-138625 and ENSMUSG00000027712 and 11747, BT.49277 and IDBG-639757 and ENSBTAG00000021746 and 281626

Gene info

• Identity
  HGNC:543
• Gene
  ANXA5
• Long gene name
  annexin A5
• Synonyms gene
  • ENX2
  • ANX5
• Synonyms
  • CPB-I
  • PAP-I
  • VAC-alph
  • RPRGL3
• Synonyms name
  • annexin V
  • Calphobindin I
  • Placental anticoagulant protein I
  • Vascular anticoagulant-alpha
  • endonexin II
• GenBank acession
  • U05770
• Locus
  4q27
• Discovery year
  1989-05-31
• Entrez gene record
  308
• Pubmed identfication
  • 2960376
  • 14678296
• RefSeq identity
  • NM_001154
• Classification
  • Annexins
• VEGA ID
  OTTHUMG00000133034
• Locus Specific Databases
  • LRG_606

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products