Recombinant Human ALDH1A3 / RALDH3 Protein (His tag)
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Catalog number
PKSH031051-20µg
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Price
Please ask
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Size
20µg
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Synonym
ALDH1A6;ALDH6;MCOP8;RALDH3
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Activity
NA
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Sequence
Ala 2-Pro 512
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Fusion tag
N-His
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Accession
NP_000684.2
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Expressed Host
E. coli
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Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
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Purity
＞96 % as determined by SDS-PAGE
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Endotoxin
Please contact us for more information.
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Stability and Storage
Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Mol Mass
57 kDa
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AP Mol Mass
57 kDa
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Formulation
Lyophilized from sterile PBS, 0.5M NaCl, pH 8.0
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Background
Aldehyde dehydrogenase 1 family, member A3 (ALDH1A3), also known as Retinaldehyde dehydrogenase 3 (RALDH3), which belongs to the aldehyde dehydrogenase family. ALDH1A3 is a novel Cancer stem cell (CSC) marker with potential clinical prognostic applicability, and demonstrates a clear correlation between CSC prevalence and the development of metastatic breast cancer. The retinoic acid (RA) biosynthesis enzyme aldehyde dehydrogenase 1A3 (ALDH1A3) is a putative androgen-responsive gene in human prostate cancer epithelial (LNCaP) cells. The RA biosynthesis enzyme ALDH1A3 is androgen responsive and (ii) DHT up-regulation of ALDH1A3 can increase the oxidation of retinal to RA and indirectly affect RA bioactivity and metabolism.
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Conjugation
histidine
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
ALDH1A3, ALDH1A3-AS1
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Short name
Recombinant ALDH1A3 / RALDH3 Protein (His tag)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
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Label
His
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Species
Human, Humans
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Alternative name
Rec. H. sapiens aldehyde dehydrogenase 1 family, member A3 / RALDH3 Protein (histidine detection labelled)
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Alternative technique
rec
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Alternative to gene target
aldehyde dehydrogenase 1 family, member A3, ALDH1A6 and ALDH6 and MCOP8 and RALDH3, ALDH1A3 and IDBG-32178 and ENSG00000184254 and 220, oxidoreductase activity, Cytoplasm, Aldh1a3 and IDBG-191846 and ENSMUSG00000015134 and 56847, ALDH1A3 and IDBG-628582 and ENSBTAG00000009125 and 507093,534200
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Gene info
Gene info
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Identity
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Gene
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Long gene name
ALDH1A3 antisense RNA 1
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Locus
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Discovery year
2021-01-06
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Entrez gene record
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RefSeq identity
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Classification
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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