Rat GRB14 (Growth Factor Receptor Bound Protein 14) CLIA Kit

  • Catalog number
    E-CL-R0317-96T
  • Price
    Please ask
  • Size
    96Test
  • Detection Type
    Colormetric
  • Target Species
    Rat
  • Target Synonym
    NA
  • Test principle
    This CLIA kit uses the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Rat GRB14 . Standards or samples are added to the micro CLIA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Rat GRB14 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat GRB14 , biotinylated detection antibody and Avidin-HRP conjugate will appear fluorescence. The Relative light unit (RLU) value is measured by the Chemiluminescence immunoassay analyzer. The RLU value is positively associated with the concentration of Rat GRB14 . You can calculate the concentration of Rat GRB14 in the samples by comparing the RLU value of the samples to the standard curve.
  • Sensitivity
    18.75pg/mL
  • Detection Range
    31.25~2000pg/mL
  • Target Name
    GRB14
  • UNIProt ID
    NA
  • Tested Sample Types
    Serum, Plasma, Cell supernatant
  • Product Name
    Rat GRB14 (Growth Factor Receptor Bound Protein 14) CLIA Kit
  • Type
    Sandwich
  • Description
    Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • About
    Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
  • Latin name
    Rattus norvegicus
  • Gene target
    GRB14   Growth   Factor   Receptor   Bound   Protein   CLIA   Kit  
  • Gene symbol
    GRB14
  • Short name
    GRB14 (Growth Factor Receptor Bound Protein 14) CLIA Kit
  • Host
    Rat
  • Species
    Rat, Rats
  • Alternative name
    Rat GRB14 (Growth Factor Receptor Bound Protein 14) CLIA reagent
  • Alternative technique
    kits
  • Alternative to gene target
    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
Gene info
  • Identity
  • Gene
  • Long gene name
    growth factor receptor bound protein 14
  • Synonyms gene name
    • growth factor receptor-bound protein 14
  • Locus
  • Discovery year
    1996-05-30
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Pleckstrin homology domain containing
    • SH2 domain containing
  • VEGA ID
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